Long-term since, clinically from diabetes disease three partition to recognize and treating type 2 diabetes mellitus. President of Beijing University of Chinese Medicine Gao Sihua presided over the topic that, diabetes and emaciation-thirst disease of TCM is part of intersection relation but not equal relationship, and puts forward the treating type 2 diabetes -- new ideas

Based on the liver spleen and kidney in treating type 2 diabetes

Reporter Hu Bin

China's traditional Chinese medicine reported

        "Based on the liver spleen and kidney syndrome differentiation in the treatment of type 2 diabetes, can be more comprehensive, accurate grasp of the pathogenesis, etiology, and thus more effective treatment." President of Beijing University of Chinese Medicine Gao Sihua, he led the group lasted nearly 20 years and completed" the liver spleen and kidney with treatment and syndrome differentiation for treatment of type 2 diabetes clinical research" the task for the 2011 Annual National Science and technology progress award two prize. The research results for type 2 diabetes and provide a new train of thought, make the clinical diagnosis and treatment of type 2 diabetes leading, and greatly improves the disease clinical curative effect.

        Cannot complete with diabetes to understand type 2 diabetes

        In 1992 March project officially started, at that time, Gao Sihua from the Tokyo National Cancer Center hospital endocrine medicine training after his return. " After the western medicine on diabetic cognitive theory and therapy methods of learning, let me also to have to learn a new understanding of the theory of traditional Chinese medicine, on the treatment of diabetes has also produced some new ideas. I think some Chinese and western philosophy, theory can be digested, thereby forming a new mode of thinking and methods of treatment."

        Long-term since, clinically to diabetes three partition to recognize and treating type 2 diabetes mellitus. Through clinical practice, Gao Sihua found, diabetes and emaciation-thirst disease of TCM can only be partially intersection relation rather than the equivalent relation. " The most typical symptoms of diabetes is ' more than a few ', in practice, in patients with type 1 diabetes have such typical symptoms, whereas type 2 diabetes patients, 90% had no such symptoms."

        Modern medicine also from Yin heat, gas and cloudy two empty, qi stagnation and blood stasis to differential treatment, although have the effect, but this type of lack of organs positioning is not accurate differentiation, can not fundamentally improve the therapeutic effect in the treatment of diabetes mellitus. Are doctors or from the stomach from the fire, or from the spleen from wet, or from a kidney from a virtual, or from a liver from a fire to treatment based on syndrome differentiation, although different people, different views., but can not truly reflect the diabetes pathogenesis characteristics and changes, effects of the disease the clinical efficacy of the treatment.

        Type 2 diabetes mellitus disease in the liver spleen and kidney

        The pathogenesis of type 2 diabetes with improper diet, eating fatness, stomach injury; emotional or poor mental stimulation, the whole liver injury; ferritic deficiency and overfatigue hurts kidney and so on, combined with type 2 diabetes clinical features, can be considered the pathogenesis of type 2 diabetes and liver spleen kidney three dirty relationship most closely. " Whatever the reason to injury in the liver, spleen, kidney any dirty, balance of power will be gradually spread to other two dirty three dirty disease, cause is false and dampness, blood stasis, dry mixed and diabetes." Gao Sihua explained.

        Gao Sihua and his team also according to the modern medicine for type 2 diabetes pathology, physiological analysis, confirmed that the type 2 diabetes TCM pathological positioning is inseparable from the liver spleen and kidney. First of all, diabetes mainly sugar, fat, protein and other three major metabolic disorders, and according to the Chinese medicine theory, these substances are" water valley, subtle", rely on spleen operation and covering the body, if not normal metabolism, accountable in the spleen of transport of dereliction of duty. Secondly, the incidence of diabetes and growth hormone, cortisol secretion is related to abnormal, while the Chinese think of this congenital kidney, main reproductive development, so with the genetic factors related to disease and growth hormone, cortisol secretion is related to disease differentiation is inseparable from the Chinese medicine kidney. Symptoms of diabetes is one of the sugar from urine comes out, and should be blamed for renal failure of solid oxygen, and the incidence of type 2 diabetes increased with age, at 60 years of age and reached the peak, which are associated with the Chinese said old liver kidney failure coincide. Secondly, to stimulate the spirit should also be attributed to the disease cause of mental stimulation, in the condition of stress, sympathetic stimulation induced disorders of glucose metabolism. Moreover, patients with diabetes have high tendency of the existence of condensate from first to last, which belongs to the congestion phenomenon, which belongs to the traditional Chinese medicine of liver failure, qi stagnation and blood stasis. So, from the Western pathological, physiological aspects of the etiology of type 2 diabetes awareness, and TCM liver spleen kidney viscera disorders perfectly.

        To verify the new thinking of scientific research

        " The fusion of Chinese and Western Medicine on diabetes mellitus in understanding of pathophysiology and treatment based on the concept, we start from the visceral syndrome differentiation to differentiating disease location: from patients living habits, physical characteristics and causes of analysis, to which the first onset of zang-fu organs, organs of the imbalance situation which showed the most outstanding aspects, a comprehensive analysis of the liver spleen kidney three dirty disorders secondary successively and the order of priority, then from the disease of patients with Yin and Yang Qi and blood, to partial a partial failure, wet, heat, blood stasis, poison, which is more important and other symptoms were qualitatively, then Ill disease with the Senate, clear and specific syndromes and corresponding principle and prescription. Take, take into account the principle of Fuzheng Quxie, distinguish primary and secondary, coordination of treatment." After nearly 3 years of painstaking research, Gao Sihua found and put forward the TCM syndrome differentiation and treatment of diabetes must be based on the liver spleen and kidney, distinguish primary and secondary and three dirty Tongzhi Zangfu ideas.

        Gao Sihua then organized the team, has applied for National Natural Science Fund and the State Administration of traditional Chinese medicine research fund, in 2501 patients with type 2 diabetes mellitus were retrospectively investigated in this study, and the formation of the database. The application of data mining methods, the liver, spleen, kidney three dirty for type 2 diabetes main position of disease, as well as being false, evil is two kinds of disease, further in TCM angle effectively proved the correctness of the new train of thought. At the same time, in this line of thought, choosing the most common syndromes 3, and Beijing University of Chinese Medicine affiliated Dongzhimen hospital, Eastern Hospital, China Academy of traditional Chinese medicine Guanganmen hospital, Beijing Shijitan Hospital, CMU and many other units together, a multiple center clinical validation studies of large samples.

        Research team on liver and kidney yin deficiency and yang hyperactivity and mainly see partial spleen deficiency, and with the heat and stasis; hepatic stagnation and mainly see spleen and kidney cloudy two empty, and with Damp-heat of spleen deficiency and stasis; wet Sheng and mainly liver kidney deficiency, and with dampness and stasis, these three kinds of disease type, respectively, to liver nourishing kidney and liver, soothing, spleen qi, established "Jiangtang Xiaoke" 1, 2, 3. After 265 examples of effective cases clinical observation summary, in the use of Jiangtang Xiaoke three group 2 months after the treatment, each lower fasting glucose effectiveness in respectively 74%, 64%, 72%, 2 hour postprandial blood glucose lowering efficiency of around 60% in both syndromes in traditional Chinese medicine, on total efficiency rate achieves 90% above.

        This research has been peer recognition of experts: not only update the traditional Chinese medicine in the treatment of type 2 diabetes in the traditional view, reflects the traditional Chinese and Western medicine theory comprehensively and theoretical and clinical closely, but also on TCM Syndromes of type 2 diabetes mellitus and the standardization of Chinese medicine research and development is an important guiding and reference significance.

        Gao Sihua said:" on the basis of these studies, we are gradually perfected this new thinking. In clinical application, to deepen the awareness of diabetes, in order to method can systematically standardizing clinical diabetes treatment. I believe that, this method is promoted, the vast majority of patients with diabetes is a great help. Clinical study on drug treatment programme is to give priority to, but can use the train of thought of comprehensive conditioning, including diet, exercise of various aspects of therapy are based on visceral syndrome differentiation, and medication combined with adjuvant therapy."