Traditional Chinese medicine danshen genetic code

Time: 2016-04-08

Source: China's traditional Chinese medicine

Author: zhao-hui Yang

Report from our correspondent recently, China institute of traditional Chinese medicine academy of sciences, Chen sl team and QiXiaoQuan team joint institute of botany, Chinese academy of medical sciences, Chinese academy of sciences institute of medicinal plants, the university of Queensland in Australia, the United States, the United States at the university of Tennessee health science center at the university of Iowa, the university of macau, Britain sanger institute and the broad medicine group and other units, in botany famous magazine "Molecular Plant" in salvia miltiorrhiza genome-wide, marked as the genetic code of commonly used traditional Chinese medicine danshen been deciphered, to reveal the main pharmacological active ingredient of tanshinone and salvia miltiorrhiza Molecular mechanism of salvia miltiorrhiza phenolic acid biosynthesis and its regulation, promote the salvia miltiorrhiza varieties breeding provides an important basis of genetic background.

Of the project of salvia miltiorrhiza genome-wide analysis greatly promoted the salvia miltiorrhiza biology research, has supported a series of high level research achievements successively completed or published. Chen sl team and wide medicine group companies forming production, interactive, providing theoretical basis for cultivation and quality control of salvia miltiorrhiza, provide new means for innovative drug production. Series work established by the genome of pattern of medicinal plants research and application of new ideas, after the ganoderma lucidum genome reignite medica genome effect, create the medicinal model as a platform to the new idea of traditional Chinese medicine research.

Salvia miltiorrhiza to the successful completion of the genome that mixed splicing technology can significantly improve the stitching effect, can effectively promote the synthesis of secondary metabolites related gene cluster identification, prove that a variety of sequencing platform combined application has a good application prospect.

In this paper, corresponding author is Chen sl and QiXiaoQuan researcher. Shi-lin Chen of the China institute of traditional Chinese medicine academy of sciences, the world health organization (who) collaborating centre for traditional medicine, director of the ministry of education Yangtze river scholars and planning development of innovation teams, head of the "traditional Chinese medicine resources study", first proposed medica genome academic direction and carried out a large number of related research work. QiXiaoQuan for "one hundred plan" the list of the Chinese academy of sciences.