Traditional Chinese medicine clinical research base construction

The core is to form a new system to treat disease (A)

-YinChangJian shandong university of traditional Chinese medicine hospital

Since the state administration of traditional Chinese medicine raised national Chinese medicine clinical research base construction business goal, two years, the base of the work is made a lot of progress. But the greatest difficulty is specific to each patient theory system is still not formed, presenting a "knows how to do, general hindrance to the" situation. Therefore, the author of academic study of importance and the specific disease academic research contents and task outline for shallow, were beaten reference.

Academic research is the core of the construction of the base

Traditional Chinese medicine clinical research base construction is a complex system engineering, which funds, base construction of facilities, and equipment purchase, talent team construction, academic exchange platform building and realizing the information resources sharing and so on many links, and each link is directly related to the success or failure of the research base construction, are all very important.

But more, we should be aware that in Chinese medicine clinical research base construction is concerned, academic research is the real key to above, all these links are for academic research this core services, is to achieve the goal of academic research to provide talents, information and material guarantee.

Therefore, our eyes must were fixed on academic research this core not shake, seize the academic research the key not to relax, make full use of current capital, talents and information resources and make to make complete base of academic research task basis and conditions.

Traditional Chinese medicine clinical research base construction of the core task is to establish the related diseases, new Chinese medicine theory system, improve the level of diagnosis and treatment of traditional Chinese medicine and clinical curative effect, expand task function, and effective academic research is finally realize this goal and the basic guarantee.

A construction period ends, when we evaluate the base construction, not only to see base scale, see team construction, see the basic condition equipment conditions, the more to see base bear related disease TCM clinical research are truly was born "could see and use, stand before, pushing open a" innovative research; Not really put forward the new theory, new methods, founded the accumulated the new experience; And these research results are clinical guidelines, truly, truly, service, and in improving the clinical diagnosis and treatment level and the clinical curative effect of traditional Chinese medicine, expand the service function of traditional Chinese medicine plays an important role. This is the most important, the only way to the academic research, it is of enduring significance.

If the 1950 s have compiled the higher education of TCM colleges published materials of traditional Chinese medicine clinical science really completed the overall framework of the construction of the traditional Chinese medicine academic progress, and on a landmark works; At present, Chinese medicine clinical research base construction of academic mission was to build modern medicine for traditional Chinese medicine difficult diseases (especially major disease) new theory system. This system is completely and accurately reflect the essence of traditional Chinese medicine characteristics, and want to accord with modern medicine the rules of the development of the disease; Maintain the main body status of traditional Chinese medicine, and fully reference for the latest achievements of modern medicine, traditional Chinese medicine and can really in the prevention and control of the major disease should play a role.

Construction of new Chinese medicine theory system related diseases

Construction of the complete system of traditional Chinese medicine theory system is mainly embodied in the following respects.

Establish related disease TCM etiology of belonging

At present the base of bear's disease (western medicine of the concept of ownership) TCM etiology is not consistent, some know even exist great formulation respectively, the main reason is expounded in understanding and traditional Chinese medicine etiology was not fully the development law of both western medicine disease.

Such as hepatitis b etiology for hepatitis b virus invades the body, through the complex caused by the immune response. TCM etiology ownership is must have the external infectious pathogenic factors and internal disease conditions. The external pathogenic factor has material, pathogenic, pathogenic specificity, infectious and latent infection characteristics such as way; The condition is internal imbalance of traditional Chinese medicine physical factors is immune. According to the standard, traditional Chinese medicine "miscellaneous gas" will be as traditional Chinese medicine etiology of hepatitis b is suitable of current research institute, and agreed that "poison" epidemic disease not accurate enough. As for the "hot", "evil" and even "poison" obviously doesn't have the sentiment, the above conditions as hepatitis b the cause is not appropriate.

Be like again, most hypertension literature from paying attention only to dizziness for traditional Chinese medicine, liver disease and syndrome argument will be Yang hyperactivity, such as dynamic as cause within liver-wind hyperactivity, and for too much salt into this important reason but every many omissions or ignored. Obviously, it is not comprehensive. In fact, Chinese medicine knew to food is too salty, easy cause blood changes, such as the constant word said in "honest"... blood and salty phase to the coagulation of blood clots, is dry ", this and hypertension common blood clots, infarction ischemic diseases such as quite well, therefore, should a salty or excessive had into salt as hypertension major cause of traditional Chinese medicine.

Therefore, further study on TCM etiology, in accord with modern medicine scientific idea of the genetic disease law, really established the related disease TCM etiology ownership and the consensus needed to establish, and even the entire clinical studies all have very important significance.

Explore the phases of evolution of traditional Chinese medicine pathogenesis regularity

TCM pathogenesis research content mainly includes two aspects. One is to hepatitis, high blood pressure, coronary heart disease, diabetes and related disease occurrence, development and natural grasp of the rules of the general. Two is to study and grasp the phases of TCM pathogenesis evolution rule.

Overall the research contents of pathogenesis regularity is multifaceted, such as foreign pathogenic factor intervention, the basic diseases, and a viscera of produced widely pathological effects and consequences, imbalance between Yin and Yang, qi and viscera function disorder, the pathogenesis mechanism and significance happens, hot and humid, sputum turbidity and blood stasis, etc pathology sex product reasons and the pathogenesis of the effect of the outcome.

The clinical research base for the course of the disease are longer, involves different pathological stage and the clinical stages. Such as hypertension can put on target organs are divided into the influence degree of the first and second stage, and the third phase; And hepatitis b is acute hepatitis, chronic hepatitis, chronic hepatitis and mild, moderate, and severe cent. So, pathogenesis of traditional Chinese medicine, had the evolution stages rules and in chronic hepatitis is concerned, the pathological changes were often in liver, the early first spleen and kidney, finally, after lead to blood inverse mess, is virtual reality and the end of them; Damp and hot blood and is in the process of disease stage pathological product. In these different disease stage in the evolution of the traditional Chinese medicine, pathogenesis regularity decided the different syndromes performance of traditional Chinese medicine, clear in the evolution of the pathogenesis of these phases, will help us law in time to take the right of traditional Chinese medicine, and making appropriate intervention measures the phases of treatment, which block disease to progress to the disease.

Research also clear influence pathogenesis mechanism outcome of the three important factors, namely the strength of the pathogenic factor degree, constitution difference and proper treatment, these three points for the influence of pathogenesis outcome trend is decisive.

Research group syndrome of distribution and performance characteristics

As the disease syndrome external reflect, it is the basic foundation of Chinese medicine diagnosis and treatment. Viral hepatitis, high blood pressure, diabetes can have DuoZhong symptoms and signs, complicated syndromes, these syndrome and because of the disease clinical types and different stages in nature, the degree, the frequency and duration, etc and have very big difference.

The study of traditional Chinese medical syndrome main task has two, one is further discussed syndrome happened, this paper discusses the essence of biology syndrome and certain diseases lesions essence and objective of the existing indices abnormal extensive connection and correlation, so as to promote the standardization of the card, objective research on, so that the research into the deeper level. 2 it is observed in some disease system different stages in the group of syndrome features and distribution. In-depth analysis constitution difference and environment, climate, feeling the disease such as many of the factors among themselves, the effects of the syndrome happened maximum excluded patients for age, sex, occupation, education and so on the different are the result of subjective symptoms to the difference of perception and expression, summarized different disease gradually different clinical syndrome types and syndrome learn range, which for correct differentiation points to provide syndrome type according to learn.