From the poison of gouty arthritis etiology

-and shandong university of traditional Chinese medicine on good affiliated hospitals

Gouty arthritis acute onset appear more severe thermal pain, joint swelling intensifies, patients often at night to endure pain with medical treatment. The clinical, ask such acute onset of the disease, most of the patients with diet, often eat seafood in related, liver or after drinking, or is fatigue, happened after violent campaign attack. These factors to trigger the TCM theoretical terms, from exogenous factors of internal injuries and belongs to. Why pathogenic factors and internal injuries could lead to severe pain? So, the author thinks that an important mechanism is to have "poison" participation.

Poison of the concept

"Poison" in the clinical often mentioned, but what is poison, the CiYuan "do the following: (1) evil also explain, harm; (2) the pain and suffering, also; (3) of content can all yue poison victimizer on another. So, we think there is a serious damage to human body all, make the person of the pain of pathogenic factors can belong to "poison" role. It is the poison damage, just make the disease is feral, process lingering, harm alot. Found in clinical stage, the occurrence of rheumatism more for foreign poison evil and endogenous toxin factor that work together. The hot and humid mind-cold timely and the days to come and fragrant poison this is the poison, viscera function disorder causing a pathological products, such as the qi stagnant, water wet, blood stasis DengRi is long do not change, and fragrant poison is a poison inside. Therefore, "poison" by evil is in essence a depressed and don't understand long but in the aggregates. This is especially clear in it, and the "poison, evil will carry your" the mystery."

From the modern medical Angle, rheumatism the foreign of poison, at least include all foreign can lead to infection pathogenic microorganism such as bacteria, viruses, mycoplasma, chlamydia, etc.; And the poison of endogenous are mainly refers to the body by various metabolic components, such as too much all kinds of antibodies, the circulating immune complex, blood, blood fat and blood sugar, uric acid protein decomposing content, etc. These days the overdose of substance will cause the body will damage, appear different system disease. So at this point and the Chinese medicine "poison" similar significance.

Poison of the source

The source of the poison both inside and outside points. External cause is cold and dampness evil influences such as yu and into poison, internal cause major responsibility in the viscera function disorder. In gouty arthritis internal cause of the poison poison is produced in a more important role. Detailed, poison mainly comes from within in the following three ways.

The spleen and stomach, endogenous turbidity lost company poison

The disease most patients had GaoLiang thick flavour, fine wine dads scoffing fatness and spicy xing greasy product of spleen and stomach, influence function, not to the ShengTan could and stuff is wet muddy poison. The department of health, spleen and stomach, time QingYang turbidity Yin not do not rise, food subtle slipped from cloth, stay to lose, be wet muddy needed. Born in poison into provided the foundation, thus become a source of poison born. Wet muddy and influence the rise and fall of angry machine, lead to gasification and promote the ability to drop, ShiXie increased production. ShiXie of heat from the sun, forming the evil day long damp and hot, damp and hot turbidity poison from birth. Hot and humid turbidity poison sticky be bored with sluggish, immersed channels, have lower limb joint especially big toe joint severe swelling thermal pain.

Renal lost opening and closing, making life turbidity poison

Normally, through the intestines of functions, such as the spleen, stomach drop/clear turbidity and small intestine secrete don't QingZhuo urinatinganddefecating and kidney function, the body's metabolism product can timely eduction body outside, not harm the accumulation. Such as imbalance of Yin and Yang, again to ferrite functions to invade, or diet LaoJuan sentiment that is wounded, aggravating viscera function disorder, unable to will metabolites eduction body outside, can be a poison, harm public will carry your body. Viscera function in the company, especially in renal loss is the most important opening and closing. Renal company opening and closing, open the excess water is fluid and metabolism product into urine; Close my body might be needed, the body fluid inside body physiological role in play. Such as the weak, or kidney turbidity poison embodiment, consumption of blood, kidney injury of gasification adverse, opening and closing, the turbidity poison to leave and not, deep v blood, to be opportunists.

The sanjiao adverse, QingZhuo mixed

Physiological conditions, water metabolism rely mainly on the sanjiao gasification and lung, spleen and kidney function of three dirty activities. The sanjiao gasification mission is to form a muddy poison lost the main pathogenesis. The sanjiao Lord of the body, for gasification company internal organs of government function, the operation of the body fluid is water line, gasification channel. Sheng is especially important if needed, the function, the QingZhuo has no right to secrete don't function with subtle use is not divided, turbidity with blood, become stuff in the note was the source of turbidity poison. At the same time, the redundant under-focusing the waterway impassability fluid and metabolism product can't timely eduction. Such as "the holy jiqing, total record phlegm retention series of" said: "the triple warmer, the function of road, gas also always triple warmer, recuperate the tone. The flat, can promote well drilling fluids.the matrix liquid, line at the, the becomes the whole blood, irrigation. If the sanjiao air plug, veins road closed to warm, the water for drinking, and may not XuanHang product, together as phlegm retention." Day long, spleen and kidney function decline and triple warmer one, is formed LongBi, GuanGe edema, such as card.

Acute episode etiology

Viscera product hot, toxin factor, encounter in v for touches, poison attack of joints

Patients have had food GaoLiang thick flavour, fine wine spicy product of be bored with her, lead to heat poison, hot and humid fell on the body toxin factor, or because of renal lost opening and closing, the sanjiao negative cause turbidity poison not out of body. The toxin factor of incentive in v is make, be gout repeated attacks of basic reasons. Just as in the gold it especially, want not wing "in the bi said:" hot, hot at close of the zang-fu organs and meridians, first... regenerative heat, and complex wind chill in the guest, hot for moisture depressed, not the cold air, the long cold also turn heat, 熻 paralysis, however, is frowsty also ". Therefore, the disease is the root cause of YangCheng ferrite and visceral product hot accumulate poison. Poison v of blood, if no evil, in general only for its dark consumption, it is lighter, qi harm In case of external causes, such as western medicine emphasizes its local joint trauma, shoes tight, sports, eat seafood, drinking alcohol, overworked, the factors such as when its internal and external photograph, its external cause in the muddy poison v block context, do not free blood for stasis. Camp to promote blood gas line, aggravate stasis sluggish, the pain in the night, a worse.

Hot poison the body fluid, suffering stagnation, blood clots and stuff for the stasis ShengTan stasis

Hot days, more heat poison gas heavy injury Yin. To promote qi, blood, blood clots operation for stasis; Yin deficiency is the body fluid, without KuiHao filling operation, may also affect each other of blood stasis. The body fluid, stagnant qi lost for the wet cloth. ShiXie burning hot smoked, condensing is phlegmy. Phlegmy wet with each other ", is angry machine can't. Phlegmy wet and blood stasis and stay together in skin, outside Cou texture, further to the bone, Jie tunnel, which ultimately leads to deeply touching refractory. And once the phlegm and blood stasis, block will appear different clinical symptoms. Resistance to Cou muscle, vein stasis, skin resistance and lost, the dark purple skin; "In the bones and muscles, joints, then see a sluggish joint swelling, nodules, deformity, expand, not even deformation, etc; Phlegm and blood stasis, and does not come loose for kidney, and hot poison, influence function abnormality jonadab, obstruction waterway, the stone is formed LongBi drench, etc.

Break etiology

V poison implication, biding momentum

After the acute phase ease, the patient that break into. During this the patient had mostly joint swelling and pain, or only mild joint pain, do not affect a patient's life and work, and very few people see a doctor. But this period in DuoZhong factors to stimulating lead to disease attack, into the acute phase stage. Will tell from Chinese medicine theory, break phlegm and blood stasis and pathological products such as hot poison in the left still inside, but due to the extent of the attacks have not yet reached cause, or no specific factors to trigger disease, make concealed, normal appearance. But phlegm and blood stasis and poison, not all damp and hot to stay in the blood, and become v poison. V poison in case of six evils that led, or for functions, diet, seven emotions ultra dishonor exertion disorders, once again, the factors touches or further aggravating, or cause his disease. Combined with the modern medical gout patients usually have high uric acid of the characteristics of abnormal blood test, we will these more blood into the "v poison uric acid category of", so the break, the doctor of traditional Chinese medicine's another idea is the traditional Chinese medicine treatment by adjusting the Yin and Yang, promote redundant, reducing the discharge of uric acid disease recurrence.

Poison v day long, wounding of righteousness

The patient sick days long, gout in not more, v poison gradually consumption injury of righteousness. Combined with the characteristics of disease, upright is the later stages of the disease, especially with qi why performance. The majority of patients form a recession, telling muscle weakness, facial color of skin dark and gloomy, DuanQi, lumbar debility, sweat out limb, the disease is still cold worse. Combined with the viscera lesions especially by the spleen and kidney is given priority to, first days and the relationship between the day after tomorrow, the illness when does not affect the heavy from the dirty. Kidney empty is pure doesn't close the solid, subtle, urine and go on from the proteinuria; Qi is what, kidney failure, Yang Yang transpiration gasification fluid ability to drop, the water flooding in the extremities, wet stay, chest and abdomen, face is edema, the person that weigh is LongBi, GuanGe; For each use, qi deficiency of qi, blood couldn't have blood deficiency without angry. The qi, Yang also gradually failure, who also insufficient blood deficiency Yin. YinSun day long, involvement in Yang; Yang loss, long, involving in Yin Yin and Yang, qi and eventually all failure. Vital qi deficiency, and are more likely to stay sluggish, turbidity poison susceptibility, aggravated damage and functions.