Phlegmy heat treatment clear

injection HFMD curative effects

     Multiple preschool children's hand, foot and mouth disease, main show is hand, foot and mouth and other parts of the maculopapule, herpes, a few cases can appear meningitis, encephalitis, brain myelitis, pulmonary edema, circulation, the obstacles to the death of brainstem encephalitis and main neurogenic pulmonary edema. The disease patients and recessive infections are mainly through the digestive tract infection, respiratory tract, contact and close the way such as communication. The disease of infectious diseases, as long as it doesn't self-limiting progress for severe cases, most of the patients a week or so can heal, and the prognosis is good, so treatment research will often children antifebrile time and skin rash fade as curative effect according to time.

     Phlegmy heat qing injection is by the radix scutellariae, bear gallbladders powder, horns, honeysuckle, such as traditional Chinese medicine tastes of all. The drug make medicine directly into the blood and a faster onset. The in vitro studies show that, for the drug, second hemolytic streptococcus pneumoniae, staphylococcus aureus, etc DuoZhong pathogens are better inhibition effect, and can be directly restrain virus, reduce the influenza virus infection of the lung mice mortality and homogenate virus blood clots drops degree; Influenza virus infection in mice can improve immune function and indirect antiviral action play. In 2009, phlegmy heat qing injection was listed on the Chinese medicine control hand, foot and mouth disease clinical technology guide "drug treatment.

    Phlegmy heat qing injection and disease-resistant poison combined application curative effects

    In 2010, guangdong province on 4 to 8 LvChongJiang medicine hospital doctors and HuangLi doctors to combine traditional Chinese and western medicine in guangdong hospital first branch of sand diagnosed type hand, foot and mouth disease cases of children of the hospital to intravenous phlegmy heat qing injection joint antivirus treatment, and has obtained the certain effect.

    Selection in April 2010 to August 2010 guangdong medicine hospital sand conforms to the standard of undiagnosed head branch of children with hand, foot and mouth disease 60 cases, randomly divided into treatment group and control group each 30 cases. Two groups of children in sex, age, duration, time to get serious condition, temperature and degree of comparison, the difference was not statistically significant. At the same time, and all of them were in phlegmy heat qing injection and chooses disease-resistant poison no history of allergies and allergic phenomenon.

    Two groups of children is assigned a conventional rehydration, such as fever treatment, to the merger with antibiotics and infections. The treatment group vein to give phlegmy heat 0.3 ml/kg qing injection/d ~ 0.5 ml/kg/d, adding 5% or 10% glucose liquid 100 ~ 250 ml of intravenous drip, the biggest dose not more than 10 ml, and giving some disease-resistant poison 10 ~ 15 ml/kg/d, adding 5% or 10% glucose 100 ~ 250 ml of bit vein, 2 times a day, according to the circumstances of water electrolyte disorder, or correct 5 days. In the control group to give intravenous drip and treatment group the same disease-resistant poison 10 ~ 15 ml/kg/d, 2 times a day, and repeat for 5 days.

     Curative effect evaluation standard according to the clinical disease diagnosis by improving standard of cure, when the drug worked with hypothermia and skin rash subsidise time to evaluate the curative effect. Antifebrile: 1 ~ 3 days for improvement, four to five days for better, more than five days for invalid; Retreat rash: 1 to 3 days for improvement, four to five days for better, more than five days for invalid. Powerfully: temperature returns to normal, oral ulcer and brothers herpes subsidise, general normal, the children have no other complications; Effective: basic normal body temperature, oral ulcer and brothers herpes, but did not significantly reduce completely resolve, general condition improved, no other complications; Invalid: treatment 5 days later still fever, oral ulcer and brothers herpes resolve is not apparent, appear other complications. Other complications treatment is to point to appear in the process of pneumonia, encephalitis, myocarditis symptoms and signs.

     The results show that the total effective rate of the treatment group and control group in 83. 3% of the total effective rate was 56.7%, a statistically significant difference between the two groups (P < 0.05). In antifebrile and skin rash resolve aspects, the treatment group in 18 cases (60%) to medicine 72 hours after antifebrile, rash away, whereas the control only 9 cases (30%) to the drug fever within 72 hours away, two groups, rash had significant differences. In addition, both groups do not have allergic reaction and other harmful response. Show that phlegmy heat qing injection joint antiretroviral therapy hand, foot and mouth disease, not only can reduce disease-resistant poison resistance and incidence of side effects, still can obviously reduce the period of treatment. At the same time, no skin rash, shivers, fever, the injection site pain, the adverse reaction.

    Phlegmy heat qing injection retention enema curative effects

    Shandong Qingdao JiaoZhou central hospital MaHongJun, SunLei, talk about XiaoJie doctors using phlegmy heat qing injection retention enema infant hand, foot and mouth disease treatment 90 cases, and found that the method is effective treatment of hand, foot and mouth disease fast, small and systemic response equipment and other characteristics, still less the children not easily overcome problems such as feed take medicaments, and easy to operate.

    Are all shandong Qingdao JiaoZhou outpatient center in hospital and children, and in compliance with the hand, foot and mouth disease prevention and control guidelines (2008 edition) "diagnostic criteria. Among them, the male 48 cases, female 42 cases; Age < 6 months 11 patients, 6 months to 1 years 34 cases, 1 ~ 3 years old (45), 69 patients with fever.

     Give phlegmy heat qing injection 10 to 20 ml warm to 37 ℃, retention enema 30 min twice a day, every day. 5 ~ 10 d for a period of treatment, and according to different symptoms children to antifebrile, anti-infection, rehydration symptomatic treatment such as support. According to the national ministry of the drugs in clinical research guiding principle "judge curative effect. Judge: powerfully, the treatment effect of 5 ~ 7 d, antifebrile, oral ulcer and herpes are disappear or basic disappearance; Effective treatment, seven to 10 d, these symptoms disappeared basically, oral ulcer basic healing; Invalid, the treatment of 10 d, above symptoms, signs were not significantly change or worse.

    The results showed that 80 cases were markedly effective, 8 cases effectiveness and effective in 2 cases, the total effective rate was 97.8%. Fever disappeared time average 2.68 + 1.33 d, herpes disappear time an average of 4.42 + 2.31 d, oral ulcer disappear time average 3.18 + 1.65 d, cure time average 4.21 + 2.37 d. With no adverse reaction. (WangNa)