Chinese herbal medicine to treat cancer research situation

Sources: the world needle league secretariat

PiaoBingKui

China academy of traditional hospital gate

Ancient Chinese have known to the tumor, from ancient huangdi to modern times in Chinese medicine books, there are a lot of description to the tumor. Two thousand DuoNian with Chinese traditional medicine to treat cancer has accumulated valuable experience. Nearly 40 years, Chinese traditional medicine to treat cancer extensive research, has obtained some achievements. Today's cancer treatment, surgery, radiotherapy, chemical treatment and biological immune therapy. In China and Chinese medicine treatment, this is the biggest characteristic of cancer prevention and control China one of the traditional Chinese medicine, widely used in cancer patients.

Traditional Chinese medicine to treat cancer has the following: (1) reduce the utility of cancer patients all kinds of symptoms and signs, improve the immune function of patients with cancer and other function condition; (2) reduce chemotherapy, radiation therapy, the side effects of speed recovery after surgery for cancer patients constitution; (3) improve the life quality of cancer patients; (4) improve chemical treatment and radiation therapy effect; (5) inhibit or delay tumor growth; (6) extend cancer patients live.

In Chinese medicine therapy and west medical method, namely chemical treatment and traditional Chinese medicine treatment, radiotherapy and Chinese medicine therapy, surgical treatment combined with Chinese traditional medicine treatment. And many later, western medicine therapy in patients with a long time after treatment with Chinese traditional medicine. Combining traditional Chinese and western medicine treatment of cancer is unique, and has China began to attract the attention of foreign scholars.

At present Chinese medical treatment for cancer use method and way to have the following several aspects:

1, in traditional Chinese medicine theory guidance and treatment based on syndrome differentiation principle, according to patients with disease to plant, symptoms and the body's condition's. We often said "the combination of disease and syndrome differentiation" combination. For example, patients with lung cancer surgery often appear sweat out evil, wind and shortness of breath wait for a symptom, card to belong to the vitality, who damaged with solid, with yupinfeng flavored: astragalus, white atractylodes, wind, calcined keel, calcined oysters medicine, water frying, and promote recovery take effective patients, can advance the use of other therapy.

2, to use the traditional medicine, and the ancient records treatment of cancer effective or modern experimental proof have certain cancer-fighting drugs. For example, yellow pill, the plum flower rhinoceros point for breast cancer and tongue Dan esophageal cancer; Angelica aloe pill treatment chronic myeloid leukemia effective; Bolus of 6 flavour glutinous rehmannia treat esophageal epithelial cells in 92 cases of severe hyperplasia, 1 years later epithelial cells to normal or to normal transformation to 82 cases, and the significant difference of than control group, 57 cases followed for 5 years malignant transformation rate was significantly lower than the control group, that is, to prevent esophageal cancer. Change role

3, traditional Chinese medicine theory and modern medical research, and on the basis of the development of traditional Chinese medicine oral agents. This is the most current form. For example, benefit spleen renal tablet (dangshen, white atractylodes, about the son, and content of the glossy privet, dodder, psoralea corylifolia, etc) and chemotherapy treatment combined with gastric cancer patients, improve the postoperative chemotherapy effect, reduce the side effects of chemotherapy, and improve the patient's immune function, prolonged survival. Phase III in 103 cases of gastric cancer postoperative chemotherapy plus this drug result, three years of survival rate of 79.4%, the 5-year survival rate was 55.3%, and the general for 10 to 30%. We developed the oral medicine of the ointment "lung tumor smooth paste", through the phase 2 clinical observation proved effective in treating lung cancer, choose the 379 cases of late primary non-small cell lung cancer, random points 3 groups, pure Chinese traditional medicine group and chemotherapy combined with Chinese traditional medicine group in the life quality and improvement of symptoms, NK cell function, are better than the pure chemotherapy group. Lung tumor flat ointment in medullary hematopoiesis function, liver and kidney function no obvious side effects, chemotherapy combined with Chinese traditional medicine group than pure chemotherapy group less toxic and side effects. Lung tumor flat paste in another group of late primary non-small cell lung cancer clinical study, confirmed that one, two years of survival rate is better than pure chemotherapy group.

4, with the basis of the theory of traditional Chinese medicine of extraction process prescription, made the injection. For example, born scattered veins injection (ginseng, dwarf lilyturf, fructus schisandrae), and share the chemotherapy treating cancer patients can increase the curative effect. Clear open spirit is Chinese traditional medicine injection developed concerning composition, and can be used for intravenous injection hepatocellular carcinoma patients and a cancerous tumor patients have certain curative effect. Crow courage emulsions courage by the crow developed with intravenous injection extract, from lung cancer patients with brain metastases, has obtained the certain effect. The newly developed by Chinese medicine injection, li is YiRen kindhearted artist vein, extract injections of patients with lung cancer, inhibit tumor, effectively improve immune function, this drug used for the effect of before surgery patients with lung cancer, through the postoperative histopathologic observation of tumor that superficial tumors have inhibition lesions.

5, made of traditional Chinese medicine for external use superficial tumors have inhibition lesions. For example, skin cancer net (red Pi, hair, nail, big jujube, fire and into), a total of 754 cases of skin cancer treatment, has good effect to the following 5 cm in diameter, the effect is better. "Expanded" (BaiPi, alum, XiongHuang, myrrh, etc.) to treat cerical cancer in 150 cases, to put the medicine insert intracervical, make tumor fall off, all effective, and survive at least five years.

6, effective in Chinese medicine extraction from the effective components, used to produce drugs clinical won a very good effect. For example, green Diane extracted indigo jade red (Indirubin), the treatment of chronic myeloid leukemia have apparent curative effect; Recently in chemical structure and biological activity based on the study of the relationship, developed a new drug indigo vision (N-methyl-lisoindigotin), the treatment of 134 cases of chronic myeloid leukemia, completely ease 32.1%, 48.5% of ease. For activating blood circulation and eliminating stasis from the extracted lam shows sweet ene (b-elemene) made lam sweet ene emulsion injection (elemene emulsionInj.), the treatment of carcinoma hydrothorax effective. From marin son extracted a son, marin (risgunone). From the CiGu extracted autumn narcissus amide (Coclchicine amide), effective for breast cancer. And as xi xi alkali extraction tree tree (camptothecine), and developed or hydroxyl trees bases (Hydrocamptothicine), the treatment of liver cancer and stomach cancer effective. And from our country mainly produced three pointed the Chinese fir extracted three pointed Chinese fir ester base (Harringtonine) and three pointed ester base (Homoharringtonine), in the treatment of acute myeloid leukemia have apparent curative effect of acute lymphocytic leukemia, and effective. Other like winter ling grass grain (Oridonin), Gambogic acid (Gambogic acid), Cantharidin (Cantharidin), bitter and alkali (Matrine), han and has a meal (Tetredrin) is from Chinese traditional medicine extracted from the effective anti-cancer properties.

These results is doing a lot of clinical practice and experimental animals on the basis of the obtained and confirmed. At present the anti-cancer mechanism in traditional Chinese medicine, has deep into the cell biology and molecular biology of level to study. For example TCM can DNA or topology heterogeneous enzyme I (DNA-topoisomerase-I) and the topological heterogeneous enzyme II (DNA-topoisomerase-II), inhibit cancer gene (Oncogene) to promote cancer cell Apoptosis (Apoptosis), etc.

Chinese herbal medicine to treat cancer features regulation and mobilize the body function, increase the body's ability to fight, so don't like surgery chemotherapy and radiation that serious damage to the body. Therefore, Chinese herbal medicine is more suitable for patients with adanced cancer can't surgery and radiation and chemotherapy after surgery break and monitoring patients.

Chinese herbal medicine in cancer prevention and restrain cancer cell to the transfer of the research also began to pay attention.