How to reasonable use of Rhubarb in treating chronic renal failure

Zhang Baodong in Handan Fourth Hospital of Hebei Province

China's traditional Chinese medicine reported

        Chronic renal failure ( chronic renal failure ) occurred in a variety of chronic kidney disease on the basis of slow onset of chronic renal insufficiency and failure is a clinical syndrome. Chronic renal failure based on its clinical manifestations, belongs to the traditional Chinese medicine" off the grid"," Journal"," kidney fatigue"," edema"," drowning" poison", don't inverse" disease category. Chronic renal failure from compensatory stage of renal insufficiency to end-stage uremia, illness is a constantly changing process of Chinese traditional medicine for chronic renal failure, to prevent early progression has a very satisfactory clinical effect. Although the latter alternative therapies that have very clear advantage, but when combined with traditional Chinese medicine treatment, to further improve the quality of life of patients with chronic renal failure, has important clinical value. At present, rhubarb has become a specific drug treatment of uremia. " Yin and Yang Yin, as big" said:" the Qing Yang on the orifices, the turbid Yin out.", application of rhubarb to maintain the dynamic balance of purgation, turbidity, the turbid evil way, it is very necessary to alleviate the condition. The route of administration has a variety of, such as the compound decoction, taking rhubarb retention enema, and injection drug delivery.

        Chronic renal failure TCM pathological mechanisms, but is false, evil solid. Evil is subject to chronic renal failure, evil solid to gas flow, machine, water valley microscopic failure to lose, will cause righteousness declines and condition worsening, the evil out of treatment of this disease is important one annulus. " Shen Nong's Materia Medica" documented rhubarb bitter cold, main under congestion, flushing intestines, bring forth the new through the old, water valley, tune in edible, and five viscera.

        Chronic renal failure with different clinical manifestations, both with and without constipation, its application is very universal. To empty a author available liquor rhubarb, commonly used 8 ~ 15g, depending on the severity of the patients and rhubarb tolerance depends, first starting from a small dose, was observed to the appropriate dose for appropriate, generally in use with rhubarb drug, with daily stool Chang Li, defecation below 3 times.

        But note that: 1 in compound decoction of rhubarb, some patients were more than 15g stool is constipation, need with immature bitter orange 10 ~ 12g, to qi stagnation, fried radish seed or Maren 30g with splenogastric dryness moistening the intestines, or Senna 3 ~ 5g to help rhubarb nasal-gastric force, its self. When patients use of Rhubarb for too long, cold stomach caused by cold stomach pantothenic acid, epigastric fullness, vomiting, anorexia, can reduce the dosage of rhubarb, rhubarb, or temporarily to Senna or aloe, dandelion, or through the use of rhubarb and Wen Li medicine ginger combination method. In some patients with fecal slurry dilute or not hog dilute and taking a small dose of rhubarb, is more than diarrhea, upright more empty person, may not be rhubarb, can get better, renal function recovered to normal or near normal, so the rhubarb and not all patients with chronic renal failure will use the goods. The for chronic renal failure with constipation and coke taste is weak and not long-term internal cold diarrhea by serum creatinine, generally not more than 500 mo1 / L, can use the outer guide method ( i.e. enema ) to Tongfu turbidity, prescribing medicinal rhubarb amount to 20g, often with oyster 30g 10g, aconite, cinnamon 10g 18G, dandelion, decocting 2 filtered juice, retention enema on day 1 ~ 2 times, or the next day to 1, with the certification of drugs. Enema in the gut is retained within the 2H above, in order to improve the clinical treatment effect. The rhubarb powder can be filled into a capsule, daily to 0.75 ~ 3.0g is appropriate, in accordance with the daily stool frequency or dosage. In order to prevent the rhubarb cold harm, in syndrome differentiation and treatment on the basis of combined with other drugs. The raw materials for injection with rhubarb rhubarb application, avoid the bitter cold on the gastric mucosal stimulation directly, indirectly "protecting the stomach, and is more convenient, quick in clinical application.