Cold-induced febride contribution to Chinese medicine oncology and the development

ZhouDaiHan The first affiliated hospital of guangzhou university of Chinese traditional medicine

China's traditional Chinese medicine reported

        Malignant tumor is frequently occurring and NanZhiBing, the world health organization announced in 2003 in 2000 the total malignant tumor patient 10 million people, 6.2 million people were killed, it is estimated that by 2020, the global cancer rates will be better than it is now increased by 50%, to 15 million. China promulgated in 2007 38 tumor registration area was a total of 100 million people, the incidence of malignant tumor for 276.16/10, the Chinese cancer incidence in more than 3 million people.

        Academic origin and characteristic of traditional Chinese medicine oncology

        Traditional Chinese medicine oncology in Chinese medicine theory is under the guidance of the neoplastic disease research etiology, pathogenesis, syndrome differentiation rules and characteristics of health care and other prevention rehabilitation a clinic subject. The mass of the theory of traditional Chinese medicine treatment is recorded in the ancient medical scattered by women, and miscellaneous diseases under the folk prescription and medical. Yin ruins oracle has been "tumour" word record; Huangdi neijing records "yesterday tumour", "muscle tumour", "intestinal tain", "choke diaphragmatic", "accumulation" wait, the pathogenesis summarized as "camp gas impassability," "cold guest in the intestinal gas phase and defend the cardiac", "vital qi xu" and "evil wins", etc. Hua tuo the scripture-stored in "point out:" husband YongJu boils the swollen by five zang-and the storage is also poison not flow is born, not exclusively RongWei congestion will do for the hair and also." Emphasize the tumor is systemic disease in local performance. Zhongjing developed in the typhoid miscellaneous diseases theory ", the creation of a set of theory of zang-fu organs and meridians as the core of the dialectical method, establishes the Chinese medicine clinical diagnosis oncology standard, the emphasis on treatment tumor should be "view their chakras card, know what make with card, inverse rule".

        The traditional from theory to clinical practice the prosperity tumor discipline, nest yuan party "the pathogenic wait theory" to the tumor etiology and pathology, and transferred disease symptoms are reviewed; The YaoFang daughter of tang dynasty sun simiao first tumor is in more than 50 party first, has highlighted the insect drugs, virulent medicine, eliminate sputum stasis drugs use; The song dynasty DouHanQing "ulcers experience encyclopedia britannica refers to breast cancer" twisting mountain rock, the name within the ". Jinyuan four everybody treatment each had cancer. The Ming and qing dynasties of the outstanding Chinese scientists with the surgical rev. The xuan ", "the surgical dacheng", "the surgical card to the raw set", "the surgical method", "Richard Yue pianwen" and so on, to the tumor etiology, pathogenesis, symptoms, and for the external treatment within a detailed discussion of the internal medicine, surgery, covers gynecology, miscellaneous diseases, such as the primary liver cancer referring to "accumulation, remove lump, jaundice" medical diseases; Esophageal, gastric cancer similar "choke diaphragmatic", "stomach" disease. Chinese traditional surgery breast cancer include rock (breast cancer), stone gall (thyroid cancer), bone tumor (bone benign tumor, malignant tumor), tongue bacteria (tongue cancer), the cocoon cancer (cancers of the lip), kidney rock (phallic cancer). The mass gynecological disease referring to "remove lump", "ren", "false child", "down" miscellaneous diseases in traditional Chinese medicine gynecology. To modern Chinese oncology constantly enrich development, has set up a file in the TCM internal medicine, surgery, gynecology, miscellaneous diseases, and other disciplines who emerged as a new branch of traditional Chinese medicine clinical.

        Modern medical treatment of cancer tumors on the change, to pay attention to "disease-free survival", surgery, chemotherapy drugs and radiation therapy for cancer is the conventional method, can inhibit tumor cells that produce or remove cancer piece, is suitable for the early to mid form the stout (part may be recurrence and metastasis). And the current XianZheng cancer patient majority for terminally ill patients, or cancer or immense multiple metastases and body virtual failure, cannot tolerate surgery or radiation and chemotherapy treatment. Cancer treatment of traditional Chinese medicine on the whole situation of patients with cancer, syndrome differentiation and treatment in the recent death of cancer cells or less chemotherapy and radiotherapy and surgical treatment, pseudoaneurysm narrowing slowly, but gentle lasting effect, can reduce the symptoms, and improve body constitution and improve the internal environment control ability, make patient get improve life quality, prolonging the survival time clinical benefit, in a late in the syndrome differentiation and treatment of cancer through a "survival with tumor" is one of the distinctive features of traditional Chinese medicine oncology, long-term "survival with tumor" is far better than to seek a short time "disease-free survival" more clinical practical significance, more people choose to give up "cease, chemotherapy more than".

        Cold-induced febride books and status

        Ancient with "grass" or "herb" as a plant appellation, and in Chinese medicine and to plant medicine is given priority to, the ancients in the process of looking for food, gradually found some animals and plants of medical effect, this is the origin of the drug. Because of human contact most of plants, and the knowledge of the earliest, at first looking for drugs just in plants, so the initial drug only plants. Although later and found the animal medicine, mineral medicine, but the "grass for drug this" the concept has been kept. This is the drug later called "herbal" origin. Cold-induced febride (hereinafter referred to as the "this the") for our country the first materia medica book, about books in the western han dynasty to the eastern han dynasty period. The book is the qin and han dynasties many medical summary, collect and sort out when the results materia medica experience book, is to summarize the system of Chinese herbal medicine, and established the basic Chinese medicine, Chinese medicine theory system that they happen, developing into an independent branch, modern antitumor Chinese medicine such as ginseng, ganoderma lucidum, BanMao, flea Hugh is from the this the ".

        "This the" original book for ages ago, in the northern song dynasty is about early has but still stored at. For years, medical experts have repeated in series, trying to restore the original visage. The existing "this the" have nine kinds of this series. Now see a version of, all of the Ming and qing dynasties BenCaoXue home after according to the BenCaoJing ce "as well as a great many, the new practice of material medica residual writing and the card kind of material medica, compendium of materia medica and other works of the preservation of the this the" wanted a complex text. LuFu (1573 ~ 1619) is the Ming dynasty, not far from number, the zhejiang qiantang, he wanted the specific cold-induced febride, books into by the god of wanli 44 years (in 1616), a total of three volumes, press of 3 kinds of classification. Top grade 120 species, 120 species of product, 125 kinds of things, and amounted to 365 in medicine. For the earliest extant "this the" JiYi this. "This the" is based on the classification of 3 kinds of people at that time on the drug performance, efficacy and clinical application of that, that is a life, raises a gender and cure, and toxicity can have the classification of the size. Those who lengthen your life non-toxic, as top, mostly belongs to the tonic thing, because soft and non-toxic role, it can take longer. Every block tonify deficiency disease no matter the toxic or non-toxic, listed as in product, such drugs could be two p its things, namely, having a work, and a block of the disease. All evil illnesses to give priority to, many things belong to, with poison attack coming, so not long clothing. Along with the development of materia medica branch discipline, the later development of 3 kinds of the subject classification, and constantly improve the classification of materia medica, a typical have compendium of materia medica materia medica of classification, that is, from plants to animals to people, the order, and in nature in the process of evolution by low to high evolution prescriptive arrangement.

        "This the" in Chinese medicine research and development of Chinese traditional medicine cancer oncology and contribution

        "This the" in all four volumes, roll a "sequence record" of traditional Chinese medicine and traditional Chinese medicine put forward a programmatic classical theory, such as "that will cure, first, wait till first source mechanism". "Medicine has a sour, salty, and Ian, bitter, essien, and cold, balance heat, temperature, cold, and four gas toxic, non-toxic". "Governance to hot cold medicine, put to the heat with cold medicine, food to spit it to the case, ghost Zhu method to poison poison, carbuncle swollen with boils boils tumor each with the medicine... appropriate". And lists various medical big card and tumor disease tumor as study cases, such as "the Lord of the husband of a serious illness, stroke, typhoid fever, chills and fever, wen anopheles, evil, cholera in............ (the following is a tumor diseases) strong product, remove lump... Zhu... carbuncle swollen ghost, evil boils gallae with...... this is ZongZhao western, which changes the branches and leaves, according to DuanXu to take". The traditional Chinese medicine identification, four generations, to the gas five viscera, and syndrome differentiation and treatment of malignant tumor, all follow the this the "first create a precedent.

        "This the" volume 2 to roll on the list, four under, 3 kinds of drugs, TaoHongJing in the mixing huang di "pointed out:" top grade, also are to be deployed to sent a disease, but its forces and thick, not for snap effect...; the product medicinal properties, curing illness words deep, the intellectual man fit the asymptotic said, take a thinner in those with speed, and remove to delay for slow...; age resulted in attack, the utility poison gas, a fierce and not out of the loss, the more that is a service uniform, stop." The detailed eliminate can't prove than people (such as empty green, CengQing, BaiQing, flat green, the skin green, feldspar, green Gan lakefront, reputation stone to wait), belong to heavy metal side effects is the play (like silver, lead and tin tin mirror nose, stone sulphur, etc), and clinical rarely users (such as dolphin eggs, moose, wild goose fat Fang, overwhelmed, overwhelmed, Lord kung Yin LiuChu hair, yan excrement, a hoof YiYu, etc.).

        "This the" in the drugs, the antitumor effect really or is worth further developers about 115 taste (accounts for about a third of the this the "above), including top grade drugs and taste, including ginseng, north Qi, kindhearted, ganoderma lucidum, YiRen donkey-hide gelatine etc, most in the advanced cancer used to tonify deficiency, centralizer" survival with tumor "treatment; Article 45 in taste, including algae, pigs lingya, angelica, turtle shell, bitter and etc, and is suitable for cancer for what the middle-late attack treatment; 27 taste things, including BanMao, toads, melon, flea's Hugh, «¥ bug, etc, and is suitable for early, mid cancer detoxification treatment away disease. Drugs commonly used treatment according to the above tumor can be divided into qingrejiedu (29 taste), remove blood stasis (12 taste), divide phlegmy qushi (22 taste), soft firm [(8 taste), like cures like (14 taste), centralizer tonify deficiency (30 taste) 6 types, widely used in common to the mass of the top 10 in the clinical treatment.

        "This the" in the part of the antitumor drugs for clinical experience-experimental research, clinical phases, and clear process and mechanism of the body, the available components extraction or effective part, from water decoction extraction for pills, tablets or injection, available for intravenous or arterial infusion interventional treatment etc, such as indigo blue real jade from the extraction of red to leukemia, melon meal to carry the's liver cancer; From BanMao, toad extraction, HuaChan element of cantharidin respectively made tablet or vein or share injection treating liver cancer or digestive system carcinoma, from sophora flavescens (bitter and base), kindhearted YiRen (kindhearted YiRen ester), north Qi (north Qi polysaccharide), ginseng (ginseng saponins), ganoderma lucidum (ganoderma lucidum polysaccharides) extract effective component made of soft capsule or injection of treatment to the mass, for traditional Chinese and western medicine is widely used in clinical oncology at the doctor. "This the" drug is our people for thousands of years through the clinical verification was summarized the dacheng pharmaceutical, from "this the" in the research and development of Chinese traditional medicine antitumor discusses ascendant, future research will no longer stay in the pharmacological research-animal experiment-extraction of monomer pattern, but in Chinese medicine theory guidance, and actively using modern means of science and technology, and to pay attention to the evidence-based medical basis, for the traditional Chinese medicine will start a new era of cancer research.