Coptis chinensis mainly by the party in the diabetes drug series application of syndrome differentiation

TongXiaoLin China academy of traditional Chinese medicine hospital gate

China's traditional Chinese medicine to

        Coptis chinensis in the treatment of diabetes has a long history, the famous doctors don't record "first record about Chinese goldthread" check/". "Huang variorum" that "common party multi-purpose coptis to flow field and thirst", the song dynasty the peaceful holy benevolence formulae of collateral for the first 177 prescriptions commonly used 10 gout drug, rhizoma coptidis was top sanwei; The lifeline party of 177 (/ in the door of monographs about 64, which contains Chinese goldthread prescription for 13, visible rhizoma coptidis in ancient diabetes therapy has been widely applied. The author will give priority to medicine coptis series of the party used in diabetes at various stages of development, with good curative effect, the clinical experience introduction is as follows, may help to fellow.

        Commonly used by the party a series of coptis chinensis

        The treatise on febrile diseases theory of miscellaneous diseases of the 14 containing rhizoma coptidis formula, which is often used in clinical treatment of diabetes for radix puerariae radix scutellariae coptis root soup, small in the chest, pinellia tuber diarrhea cases heart soup, rhubarb rhizoma coptidis xie xie monkshood heart soup, soup, ginger purging heart heart soup, liquorice purging heart soup, rhizoma coptidis soup, rhizoma coptidis colla soup, plum pill, dry ginger scutellaria coptis ginseng soup.

        1. Rhubarb rhizoma coptidis xie heart soup

        Rhubarb through reducing the turbidity, can clear gastrointestinal reality of the hot, guide in full. Rhizoma coptidis heat drying wet, clear gastrointestinal real hot dry the wet intestines and stomach. Rhizoma coptidis use easy make dry excrement inside knot, compatibility rhubarb through setting, prevent the defects, and can enhance the heat work. Both of two complement each other, "FuDeChouXin" to clear gastrointestinal reality of the heat.

        2. Components of gegenqinlian decoction

        Kudzu root, its taste is symplectic sex cool, can solution muscle heat, but also clear bowel heat, still can rise gastrointestinal fluid, the famous doctors don't record "speech GeGenNeng" cure insomnia ", modern research confirmed that kudzu root has the effect that reduce blood sugar. "The sex, scutellaria baicalensis georgi clears, so in addition to evil, bitter taste so dry wet; Yin cold so - heat, so the Lord the hot" (" huang drain "), and rhizoma coptidis compatibility enhance its dry wet heat of the work. Rhizoma coptidis, radix scutellariae and pleasant embellish the kudzu root, liquorice compatibility, receive "the bitter dryness of the profit without suffering the disadvantages is also" (the compendium of materia medica speculative record ").

        3. Small in chest soup

        Small in chest soup for heat polyester sputum preferred party. Pinellia tuber for eliminating phlegm to medicine, "away heart chest every phlegmy heat" full "(" don't record"). Trichosanthes kirilowii maxim real Kennedy cold smooth, good polyester sputum knot, "and in the washing XiongGe scale greasy muggy" (the typhoid card to the criterion "), for polyester sputum elimination of turbidity is tasted, the large intestine and liver release heat, runchang purge; Not only help Chinese goldthread heat purging fire, and help pinellia tuber eliminating phlegm to open ", and then run the guide. The YiZong JinJian "load:" Chinese goldthread polyester hot, pinellia tuber guide drink, trichosanthes kirilowii maxim embellish and descending, the whole of polyester XiongGe phlegmy heat, open XiongGe gas "." Small in chest soup, heat polyester phlegm to blow paste turbidity, hard to do gas in addition to the zhongzhou full.

        4. Dry ginger scutellaria coptis ginseng soup

        Ginseng nourishing spleen and enriching qi, dry JiangWen boc gas, compatibility effectively role in spleen to warm the spleen in; Radix scutellariae, rhizoma coptidis heat drying wet, the function of the stomach to clear the stomach heat. Two groups of drugs and cold temperature, the reinforcing and reducing.

        5. Pinellia tuber purging heart soup

        The Qin experience, even XinWen and the pinellia tuber, dry ginger compatibility, hard, cold temperature and suitable for symplectic open bitter drop method, the model of "bitter cold can clear away heat moisture", "XinTong can KaiQi drain cloud", "essien to open, bitter to drop", "bitter drop its inverse, XinTong the bi" (the clinical guidelines basis "), and $ginseng, liquorice, jujube nourishing spleen and enriching qi.

        6. Plum pill

        Dark plum fruit acid temperature, gathered liver wood and help faint Yin qi live, and the wind fire burning away the fear in no; Nourish "Yin" to stop insomnia; Rhizoma coptidis, cypress, heat drying wet, phellodendron especially longer than clear the spleen and kidney of the hot and humid. And even with plum, cypress, bitter sweet to system. Angelica enrich and soft liver, promoting blood circulation by removing a limb end, ginseng, asarum, shu pepper, cassia twig, dry ginger, monkshood releasing temperature cold, and the power of the main and collateral channels WenTong blame very, treatment for a cold syndrome. The whole party and chills and fever, fill the attack; And XinGan share can turn Yang, acid can be established with gump Yin. So, Yin and Yang to mediate, chills and fever can pacify.

        Rhizoma coptidis series the party application points

        "Element asked · odd disease theory" yue: "this fat have hair, this person will eat honey number and weight also. Fat person is internal, sweet person is in full, so the gas overflow, to insomnia." The author thinks that obese type 2 diabetes in full for internal core pathogenesis, disease up food depression, because depression and heat, heat loss and virtual, and ultimately from virtual to loss, form diabetes occurrence and development is deficient wind-cold four stages. The specific process: eat fatness, spleen and stomach function damage, the hysteresis of the upper abdomen and become filled with; Spleen soil supplement hysteresis, day long turn heat, sweep viscera, or with phlegmy wet bonding, for the performance of the stomach heat, intestinal heat, bravery heat, liver heat, phlegm heat, hot and humid, etc.; Prolonged illness, hot air injury Yin, the development of the virtual stage, this process many see the actual inclusion, for the performance of the spleen stomach heat, spleen, stomach perched on the hot cold, etc.; Heat, virtual stage further development, damage collaterals, appear diabetes complications, the development to damage stage. According to the characteristics of pathogenesis and syndrome stage performance, differentiation of symptoms and signs choose the party, often use cure diabetes heat, deficiency of the stage.

        1. Hot stage

        Hot stage mainly for gastrointestinal real heat syndrome, bowel, damp and hot accumulate knot phlegmy heat certificate, certificate. Rhubarb rhizoma coptidis xie xie gastrointestinal hot "heart", so use to gastrointestinal real heat syndrome, the dialectical points as a dry mouth bad breath, constipation, According to the heat, even through the intestines bowel wet, so use to intestinal hot and humid card, differentiation of symptoms and signs point to defecate viscous not great, moss yellow sticky; Small in chest "phlegm heat, so use to phlegm heat accumulate knot card, the dialectical points for new wan chest tightness, moss heavy greasy.

        2. Virtual stage

        Virtual stage mainly for spleen stomach hysteresis certificate, spleen stomach heat syndrome, under the hot cold syndrome, etc. Pinellia tuber purging heart ShangXin open bitter drop, spleen qi, disappear, so filled with spleen deficiency syndrome with cure stomach lag, the dialectical points for stomach discomfort, swelling or hiccups; If the symptoms of diarrhea, the ginger soup with diarrhea heart; Dry turmeric even baikal skullcap root ginseng soup for stomach temper clear heat, cold and warm, so use to spleen stomach heat syndrome, the dialectical points as a lack of power, dry mouth, General multi-purpose dangshen, hot like the person that weigh with American ginseng, virtual person with red ginseng; Plum pill clear on temperature, therefore, to use on the hot cold syndrome, the dialectical points as a dry mouth bitter, waist the fear of cold.

        Coptis chinensis by party a series of clinical application experience

        1. / stage not avoid rhizoma coptidis

        Obese type 2 diabetes development process as neijing mentioned, up to obesity, experience spleen an illusion of the senses, and ultimately to insomnia. The disease often insomnia stage in the mid-late period, many see the actual inclusion, chills and fever mixed card, what disease resistance by thermal transfer cold. This stage should be treated with tonic is given priority to, but if blood sugar on the high side, still can add blindly in removing of coptis chinensis, only take its hypoglycemic, and abandon the bitter cold of the sex.

        2. Chinese goldthread cause diarrhea and antidiarrheal problem

        Rhizoma coptidis bitter cold, bitter cold person hurt, so coptis can cause the spleen and stomach deficiency cold, appear the symptom such as diarrhea, and with ginger or dry ginger can be with ZhiHuang even the bitter cold, avoid experience hurt a stomach. At the same time, Chinese goldthread dry wet, but thick intestinal check flow field, so a lot of application can also cause constipation, abdominal distension, and if the rhubarb on compatibility, can avoid the disadvantages coptis thick intestines.

        3. Commonly used medicine coptis chinensis on

        Coptis chinensis franch and different drugs after compatibility can be used for diabetes muggy virtual damage each stage. Such as Chinese goldthread compatibility scutellaria, clear gastrointestinal fervent, often used in hot stage; Rhizoma coptidis compatibility rhizoma anemarrhenae or pollen, heat of give attention to two or morethings, Yin fluids for evil thermal injury Yin; Rhizoma coptidis compatibility late silkworm sand, heat change chaotic, used for wet turbid phlegm heat cement person; Rhizoma coptidis compatibility plum, clear drain hot and gathered Yin fluids, fire poison injury Yin; Rhizoma coptidis compatibility cinnamon, clear heat and temperature on the cold, cold for the mixed.

        4. Chinese goldthread dosage

        "The stipulation of" pharmacopoeia of rhizoma coptidis clinical dose of 2 ~ 5 grams, the dose range for the fair, but if used for hypoglycemic, unavoidable power is too small, in the ocean. We went through long-term practice, fish out coptis glucose-lowering dose should be more than 15 g. In general, the glycated hemoglobin (HbA1c) in 6.5% ~ 7%, rhizoma coptidis 15 grams left and right sides; HbA1c in 7% ~ 10%, rhizoma coptidis for 30 grams left and right sides; HbA1c > 10%, rhizoma coptidis in 45 grams or more. The author has put a new-onset type 2 diabetes, impaired fasting glucose 22 mmol/L and postprandial blood glucose 34.99 mmol/L, before applying hypoglycemic western medicine, application 90 grams of rhizoma coptidis treatment 2 weeks later, fasting blood sugar drop to 7 mol/L or so, postprandial glucose down to 9 ~ 12 mmol/L. In the application of large dose of rhizoma coptidis, general treatment cycle for 1 ~ 3 months, at the same time in ginger 15 ~ 30 grams or dry ginger 6 ~ 9 grams with ZhiHuang even the bitter cold, and blood sugar control standard, the coptis decrement, and change decoction for pill, powder, rhizoma coptidis daily dosage only 1 ~ 3 g.

        Summary: the application of coptis chinensis in diabetes has to clear away heat, dry wet to grow perceptibly, in view of the diabetes pathogenesis and internal filled with core wind-cold virtual damage each stage and pathological characteristics, through the compatibility, choose rhubarb rhizoma coptidis xie heart soup, components of gegenqinlian decoction, small in chest soup used in the early stage of diabetes heat; Dry ginger scutellaria coptis ginseng soup, pinellia tuber purging heart soup, plum pill used in the middle of the actual diabetes inclusion stage. Rhizoma coptidis in governance hypoglycemic, dose should be great; Use to regulate, small quantity is enough; High-dose oral glucose-lowering, applied decoction short-term treatment; Small dose maintain to pill, powder long-term conditioning. Coptis chinensis is bitter cold, but the compatibility, bitter cold nature can be assist system, and secure the injury of the disadvantages, as diabetes treatment to medicine.