From the blood stasis to explore the pathogenesis of pulmonary fibrosis

KaoXiLiang Affiliated hospital of shandong university of TCM

China's traditional Chinese medicine to

        Pulmonary fibrosis is a respiratory system diseases, including idiopathic and secondary two types. The disease once formed, are difficult to reverse, only through active treatment delay its progress. Most patients disease break out repeatedly, gradually increase, and eventually a respiratory function failure and death. For touching refractory characteristics and prognosis of the disease bad end, the author thinks that this disease occurred is an important mechanism in the process of blood stasis.

        The concept of blood stasis

        Blood stasis, as well as sedimentation, is short for blood stasis, not original meaning refers to the blood product, product is inherent in the theory of TCM pathology. For stasis, said wen jie zi "interpretation:" the blood stasis and hemorrhage." "Ci sea", "blood stasis and hemorrhage. The blood stasis. Refers to the body confined by certain premises." Sediment silting, this refers to the water precipitation, but also has the meaning of "hysteresis plug, not circulation". CiYuan said: "the silting, hemorrhage disease." General, who left the meridians unable to dissipate blood stasis in one place, and or poor blood flow, run suffocate suffocate, stasis in freeze state within the meridians and organs, are called blood stasis.

        The source of the blood stasis

        Sources of blood stasis mainly have two aspects, on the one hand, is dropped servant flash cutting injury factors such as damage to the human body channels, viscera, meridians directly lead to damage to blood don't tired, overflow in the vein for blood stasis; On the other hand is under the effect of internal factors of the consequence of human viscera function disorder after pathological products. The latter often has a more important role in the onset of the disease. In terms of detail, blood stasis mainly comes from the following respects.

        1. Spleen health delivery, phlegmy wet endogenous

        Taste is the day after tomorrow, the source of qi and blood biochemistry, blood system Lord again. Qi is the material basis for the viscera function normal operation. People of a fundamentally borrow reception rotten, stomach and spleen to transport up normal function and a steady stream of biochemistry. So when the disorder of spleen and stomach function, can affect the formation of qi and blood, run, and spread out, resulting in a series of pathological manifestations. For example patients always fond of rich men's taste, wine of fat and spicy red in of be bored with, and affect the function of spleen and stomach, not reformed, the valley to be stagnant water to wet, brew ShengTan water wet. Spleen and stomach health delivery department, long QingYang don't rise turbid Yin don't fall, subtle distribution, water stop di, breeding damp turbidity. Wet muddy often affect qi activity rise and fall, resulting in a decline in gasification and the ability to drive. Gas is blood is handsome, gas line is blood, qi and blood stasis, blood stasis. Besides spleen sun be the spirit is weak, weak blood, the blood spilled pulse directly outside of stasis. Once produced, are often linked to blood stasis phlegm wet cement mutual harm, phlegm and blood stasis indicates lag, blocking the airway patients cough cough up phlegm, chest tightness, wheezing, dim complexion, oral purple purple.

        2. The liver pathogenesis, qi activity

        Liver is just dirty, pathogenesis is Spain and storing blood. Both article of qi activity, and pathogenesis of modern, at the same time also can support the normal distribution of body fluid, bile and blood, if the etiological and dereliction of duty, everything which is born. Patients usually found in modern, sorrow is hushed into gas knot, or depressive anger hurt liver, cause liver pathogenesis of qi activity stasis, stasis, long, there will be a different shift. A shift is driven by qi and blood running to produce a decrease in the ability of blood stasis; Another change is the gas YuRi long fire, heat in blood stasis or forced: blood spilled blood vein of blood stasis. Liver does not blood, blood lost, hidden, it is easy to become stagnant blood stasis blood. Blood stasis of tangible goods, can increase qi activity block, which can lead to disease cycle.

        3. A better mousetrap, push

        Heart god, main veins. The normal operation of the blood first rely on building a better mousetrap. If insufficiency in patients with quality, weak or frail, long illness are injury, leading to a better mousetrap, encouraging blood weakness, poor blood running, is blood stasis. Blood stasis is formed and in turn can affect the person XuanChang, leading to Yin jin sun be the spirit hard buda, lung moist, further aggravating illness. Many patients clinically, the disease regardless of symptoms and signs, or laboratory has blood stasis, such as methyl violet purple facial dull, lip, erythrocytosis, increased blood viscosity, etc., late or even affect the right heart function leads to right heart function not full-time, congestion, etc of the systemic circulation in obvious signs of blood stasis in TCM.

        4. Lung qi, disease and in the blood

        Lung main gas, breathing, lotaustralin section chief, lung or his dirty long illness involving in lung disease can lead to pulmonary qi deficiency. Cases of gas penetration cardiopulmonary and breathing, heart pulse flux in lung, heart and lung two dirty. Lung qi deficiency is not governance regulation rather than run, lead to "main" operating overfatigue, head and heart Yang deficiency, promote blood to the blood line of sluggish acerbity, cardiac nervous, pulse generation, and nail bed purple purple in your lips, and neck pulsating like of qi deficiency blood stasis and so on.

        5. Five losses, qi and blood no longer, long illness into the network

        Internal injuries patients, seven emotions, diet, LaoJuan attempt indicates, sick for a long time will hurt upright, lead to five losses, qi and blood deficiency, collaterals emptiness, pathogenic ChengXu invade collaterals. Ye Tianshi said "the main gas, winding the blood", "at the beginning is in the air, the long blood wound into the complex", long illness into the theory of collaterals theory is put forward. According to ye shi by reasoning, after a long illness into the network will lead to blood stasis, and blood stasis.

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