Let the innovative Chinese medicine anti-tumor frontier

In the 2013-04-01 s, Chinese traditional Chinese medicine

        Reality, rising morbidity and mortality of malignant tumors and traditional treatment methods are often stretched thin, weak. Traditional treatments generally focus on the tumor itself, with surgery, radiotherapy, chemotherapy and other means to control the tumor. But about 60% of malignant tumors have been found in the middle-late, surgery can't solve the transfer of cancer cells to spread, radiation and chemotherapy will be normal cells to the human body and the body's immunity, gastrointestinal, liver and kidney damage, bone marrow hematopoietic function, etc.

        To the treasure-house of traditional Chinese medicine (TCM) to explore "their thinking," create "new weapon" from the Chinese herbal medicine, starting in the 1980 s, has been working on conquering Xie Tian exploration of cancer drugs. A group of Chinese and western medicine clinical and scientific research and industry experts to join the team, there is no lack of among them such as Qin Shukui, Sun Yan, Lin Hongsheng, Wang Xiaomin, golden flower, Li Zejian such as you. "Lam incense ene liposomes series targeted anti-cancer natural medicine industrialization technology and clinical application" project, eventually won national scientific and technological progress second prize in 2012, shows the importance of innovation in the field of anti-tumor Chinese medicine value.

        And family origin and the background of Chinese and western medicine of traditional Chinese medicine, clinical and scientific research experience, let Xie Tian have the unique vision and ability. He didn't leave the traditional Chinese medicine "set a thief to catch a thief, qingrejiedu" way for the treatment of cancer, but in the traditional Chinese medicine predecessors inspired, gradually has been clear about the "disorder of blood elimination centralizer, treats disease" new ideas, and using the "compatibility" theory to guide research and development of modern traditional Chinese medicine.

        He lead the team to carry out clinical and experimental research, through to the Chinese medicine anti-cancer active ingredients selection, find some non-toxic herbal essential oil has a strong anticancer activity, anti tumor has a wide spectrum and low toxicity. Followed the discovery of Xie Tian team to series of separation and purification of the volatile oil components, pharmacological screening and structure identification, excavated sesquiterpene compounds of small molecule - lam incense ene.

        Experimental study confirmed that lam incense ene is through drop model molecular distillation refining technology, the efficient low-toxicity anti-cancer active ingredients from Chinese traditional medicine extraction and separation, can be targeted liposome preparation tech packs in a class of liposome membrane of nanometer microspheres, not only can improve the stability and the slow release of drug, still can make drugs on cancer cells (targeted) stronger affinity, can make the drug slowly released from liposomes, continue to kill cancer cells, so as to improve therapeutic index.

        Clinical studies have found that lam incense ene injection can be directly intravenous drip, artery intervention, cavity chemotherapy (mouth, BiSi, atomization inhalation, drench with rinsing, filling, etc.); Lam incense ene liposomes oral emulsion taking convenient, can use for a long time, can also improve bioavailability, reduce the stimulation to the stomach, to avoid the deactivation in the stomach. Especially can selectively kill cancer cells and normal cells, heart, kidney, digestive tract, nerve, bone marrow, such as no damage, but also activate the body's anti-tumor immune function, has a "dual role".

        Widely recognized, the efficacy of lam incense ene new drugs based on internationally accepted based on evidence-based medical research. Research results show that the anti-cancer natural medicine lam incense ene treatment of lung cancer, liver cancer, brain cancer, stomach cancer, esophageal cancer, pancreatic cancer, nasopharyngeal carcinoma, bladder cancer, gynecological tumors and cancer, cancer bone metastases chest water such as safe and effective; Combined with chemotherapy or radiation therapy, can be attenuated synergies; And can prevent and reverse and molecular targeted drugs effective multi-drug resistance; Especially in improving patients' life quality, prolong survival and recurrence metastasis, etc have obvious advantages.

        In the process of achievement transformation, Xie Tian to solve "extraction and separation of mass lam incense ene, lam incense ene preparation" two big difficult problem. Therefore, Xie Tian visited pharmacy at home and abroad well-known experts and professional equipment manufacturers, and members of the cooperative enterprise research plan, collection parameter and adjust equipment, design and development of the falling film type molecular distillation refining technology and equipment, has realized from the traditional Chinese medicine extraction and separation of anti-cancer active ingredients lam incense ene of scale, industrialization, and with high yield, no pollution, low energy consumption, green environmental protection production technology won the invention patent, in the domestic set up the first through the GMP certification of liposome anti-cancer drug production line. Currently, lam incense ene liposomes series targeted anti-cancer natural medicine (jingang lam incense ene injection, lam incense ene oral emulsion) has entered the national health insurance drug catalogue.

        Clinical widely used anticancer drugs derived from plants have four categories: paclitaxel, camptothecin, vinblastine, lam incense ene, among them, lam incense ene is first in our country from its anticancer medicine found and successfully developed with independent intellectual property rights of antitumor medicine plants. Xie Tian team created lam incense ene drugs in cancer drug research and development testing resources treasure house of Chinese medicine value and ultra high "price", for the majority of cancer patients and their families, and society.

The original link: http://news.pharmnet.com.cn/news/2013/04/01/374772.html

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