Efficacy of traditional Chinese medicine does not preach decipher the secret of science

- read both xiao Lin TCM inductive and party dose effect

Wang Jian Anhui university of traditional Chinese medicine

        Since ancient times has been the secret lies in the amount "of" Chinese medicine don't preach, physicians in qing dynasty Wang Qingren also thinks: "ingredients important, more important weight", visible clinical dose selection to some extent determine the clinical curative effect of traditional Chinese medicine. Especially with the deepening of the modernization of traditional Chinese medicine scientific research today, in-depth discussion of the formulas best concentration-response relationship, will no doubt for basic research and clinical practice of traditional Chinese medicine's pursuit of "safe curative effect is stable, unified standard," the three highly unified provide a solid theoretical basis. TCM no matter inside and outside, women, in all subjects, and in principle, method, square, each level left a valuable experience for us. System research in the field of clinical doses, however, are still not enough, the doctor of traditional Chinese medicine clinical workers can only rely on the accumulation of experience in the clinical to grasp the dosage, failed to form a complete set of dose theory, the formulas of traditional Chinese medicine (TCM) to the dose of the formulas become eternal mystery.

        , professor of Chinese academy of sciences hospital gate 8, xiao Lin engaged in Chinese medicine clinical and scientific research, teaching work for nearly 30 years, he actively explore, learn to test all, in many fields have achieved fruitful results. He recently launched the party dose effect to learn book, now had the opportunity to study, so, feeling is quite deep, the characteristic and innovation of Jane column in this book, share with you my colleagues:

        Improve the vision of academic framework structure

        The book summary and the theory of two parts. General research progress party dose effect relationship were discussed and the key problems and strategies. The theory of comprehensive system from nine aspects discusses the party dose effect relationship between scientific connotation and its scientific research and the problems facing. Expounded in the book "to the human body" the dosage of the formulas of strategy and the dose of medicine "as" law, and introduces the influence factors of dose effect relationship, emphatically expounded the study dose effect to learn scientific method system and multidisciplinary cross application in party drug effect study. For dosage effect of consumption safety, save the columns such as medicinal material problem discussed made concrete, this paper finally lists the specific how to apply the dose of the formulas in the course of clinical practice, then attach to ancient and modern basis to verify that the doses of specific application.

        Its research method and perspective with high coverage and systemic, encyclopedia from the ancient and modern literature, traditional Chinese materia medica, the modern pharmacology, medicinal chemistry, metabolomics, systems biology, clinical evaluation, clinical practice and other multi-disciplinary, multi-angle in all the subjects, and systematically summarizes the dose effect to learn the main contents, research methods and main achievements, at the same time pay attention to the other dose effect to learn theoretical knowledge, scientific research, clinical practice, summary analysis of ancient and modern basis, did the theory and practice of the interoperability and interoperability.

        Research methods unique fields widely

        For "pharmacopoeia" the provisions of the state of the contradiction between the actual dosage of clinical dosage with modern, the book puts forward the reasonable to build a reasonable clinical Chinese medicine dose of the scientific method system. Using "four dimension", "five phases", "spiral ascension" research model, from the aspects of literature, clinical, toxicity and pharmacodynamics system to carry out the relevant doses of the study, the formulas from the above four aspects of the research into the integration of data mining, reasonable formation of traditional Chinese medicine clinical dose the draft, and on this based on the traditional Chinese medicine clinical experts, and quantitative assessment of the TCM expert, forming reasonable clinical dose range, then research results for clinical application. Finally, clinical recommended dose range in the clinical application of continuously to form a new literature, to supplement the original concentration-response relationship database, form the research model constantly improve, and constantly improve. On the basis of this method system, and then system on traditional Chinese medicine compound concentration-response relationship of clinical research, experiment research, literature and theory research, deep thinking and comparative study, the dose effect relationship series question has carried on the comprehensive analysis and summary law, and establish the clinical curative effect evaluation as the center, combined with experimental research and literature research of multidisciplinary party dose effect relationship on the basis of the research model.

        Modern multidisciplinary knowledge, the book also brings together organically in modern research of traditional Chinese medicine, Chinese medicine so as to realize the modern scientific connotation, dose affect the curative effect of the problem for the modern medicine of standard argument.

        Unfinished, full text links: http://www.cntcmvideo.com/zgzyyb/html/2013-04/26/content_72575.htm