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2014年05月06日
Opens the way of traditional Chinese medicine for external use blue ocean booster internationalization of traditional Chinese medicine (TCM)
07:35 May 05, 2014 source: city express author: Zhou Zhe
In May 2008, in the wenchuan earthquake relief, our country's famous professor ulcers experts Li Jing disciple surgery of traditional Chinese medicine (TCM) in the second affiliated hospital of tianjin medical university zhang zhaohui (left), director of sichuan province in the traditional Chinese guide how to use "jing Wan Gong" and "rubber ointment" treating the wounded.
On February 27, 2014, in Beijing Wan Gong JieTiHui ointment treatment of diabetic foot clinical research project, FuXiaoBing academician of Chinese academy of engineering project.
The function of Beijing Wan Gong ointment in the beginning of its approval and put into production, by the function of its approval attending "to treat water electric burns, ulcers swollen pain, wound fester" precise covers, but due to historical use habits and was impressed by the first reading, it can cure "fire, water, and electricity burns" functions are all in mind. And eighties of the last century, all the stove, hot water, the situation has happened repeatedly burn or scald, almost every necessary Wan Gong "Beijing", some still need to put on a in case of urgent need in the kitchen. But its "huoxue jiedu, acetanilide detumescence, saprophytic muscle" function, for treating ulcers swollen and painful wounds fester, namely late in wound healing, also can make the skin more perfectly and leaving no scars. Also as a result, Beijing Wan Gong ointment in the treatment of ulcers function gradually submerged condition, people tend to remember only Beijing Wan Gong ointment effect for the treatment of burns. Wan Gong ointment and, in fact, Beijing is a broad-spectrum topical proprietary Chinese medicine, its functions are not constrained by the good to treat burns, burns, burns. Based on the Beijing Wan Gong ointment anti-inflammatory detoxification, saprophytic muscle, a variety of functions, Beijing Wan Gong ointment can be widely used in trauma, pressure ulcers, diabetic foot, frostbite, herpes zoster treatment of surgical disease, etc. These are Beijing Wan Gong ointment in the wenchuan earthquake, in yushu earthquake, in the treatment of the wounded don't heal the wound long aspect shows the magical efficacy were gradually after verification. In turn, also opened the chance in traditional Chinese medicine for external use lead Chinese medicine to world. Our correspondent Zhou Zhe
Efficacy of distinguished
Disaster highlight magical curative effect
In 2008, a sudden earthquake affects billions of people, the wenchuan earthquake is one of the largest earthquake since the founding of the destructive, caused great casualties. Disaster areas in sichuan, the rescue team to the wounded, rescued from the rubble of injured late face wound infection, wound healing, and a series of treatment. At noon on May 23 a message from the ministry of health of the sichuan earthquake command center, in 270000 injured, mostly bone trauma, and at that time, his condition deteriorated, wound infection is serious, be badly in need of an effective method of treatment in TCM. If the wounded is not a good treatment and make the wound healing quickly, will face a serious situation of amputation.
Beijing Wan Gong traditional impression is generic burn ointment, has high visibility and reputation throughout the country, but its in the treatment of wound infection, for a long time does not heal, also has the very good curative effect, this is China's famous Chinese and western medicine combined with ulcers experts Li Jing professor in more than 50 years ulcers external treatment to corroborate saprophytic muscle method in clinical practice, and got the effect in the treatment of the tangshan earthquake. On the afternoon of May 23, 2008, the state administration of traditional Chinese medicine held an emergency meeting three times. Professor given Li Jing external therapy of traditional Chinese medicines have the actual treatment experience and effect of tangshan earthquake certification, thought has its treatment technology promotion and use of traditional Chinese medicine for external use the urgent need of treatment, immediately determine proposed by professor Li Jing go saprophytic muscle law - Beijing Wan Gong rot and rubber raw muscle paste combination treatment, the production of in order to solve the question wound infection, for a long time does not heal the wounded.
On May 25, 2008, the state administration of traditional Chinese medicine FangShuTing led a line of seven people, deputy director of expert committee of Chinese medicine in sichuan earthquake relief region, Beijing Wan Gong drug donations of hundreds of thousands of heads of state of consignment Wan Gong ointment "Beijing", "rubber ointment" 20 pieces of each, random to sichuan. Surgery of traditional Chinese medicine (TCM) in the second affiliated hospital of tianjin medical university, director zhang zhaohui (Li Jing disciple) as a member of expert committee, the shock injury in patients with wound infection, wound healing emergency treatment, and on-site training guidance to medical staff.
TCM external therapy for illnesses infective wound does not heal, have one thousand years of history in our country and practical experience. The treatment of early use of Beijing Wan Gong to rot, for later application rubber raw muscle cream raw muscle treatment, its characteristic is generally no antibiotics, is not subject to the restriction of medical condition, not only can quickly make the wound healing, and greatly reduce the pain of the wounded, highlights the Chinese medicine for external use in the treatment of trauma of Jane, then, effect, the advantage of the test. At the same time, the two drugs for ointment formulations, adhesion and tear when dressing the wound, the pain of the injured is greatly reduced. In seismic casualty treatment, represented by "jing Wan Gong" external treatment of Chinese medicine in the treatment of wound infection, for a long time does not heal diseases showed on magic, has caused many injuries from secondary amputations, highlights the great therapeutic advantage.
On June 18, 2008 "reference news", "a British doctor of traditional Chinese medicine (TCM) in the quake zone feel magic - was a great shock to anti-infection effect of Chinese herbal medicine", reported the UK titled "smoothing China earthquake trauma" article, tells the story of British plastic surgeon tile SIMS saeed met a lost a leg in the wenchuan earthquake, as the little girl thigh amputation, residual limb with brown Chinese herbal compound preparation, the wound has been 12 days but no signs of infection, the bandage and the little girl sat on the bed, reading a book is not the pain. The earthquake in Pakistan with him to see a completely different: treatment, there many children bear pain by paramedics removed the bandage, every day in order to clean up the residual limb. Tile SIMS saeed doctors see the brown compound preparation of Chinese herbal medicine is Beijing Wan Gong ointment.
This major event, this magical curative effect, and has reopened "jing Wan Gong" ulcers.
Expanded function
For external use of TCM, engineering center
Beijing Wan Gong ointment in the treatment of the wounded during the relief and for a long time does not heal the wound infection of magical curative effect, has a keen insight into business leaders see the traditional Chinese medicine for external use promising prospect, keenly aware of: the Beijing Wan Gong ointment in function expansion of ulcers, trauma, etc., be able to dig out the "Beijing Wan Gong" in class such as ulcers wound treatment effect, also is the implementation of the tianjin pharmaceutical group, large variety strategy and find key points in the new "blue ocean". This opportunity, China's first research and development of traditional Chinese medicine for external use transformation base arises at the historic moment.
In April 2009, tianjin pharmaceutical group and the municipal economic commission, science and technology support, by the Chinese academy of engineering, Chinese academy of sciences, in traditional Chinese medicine, tianjin, led by the university of Chinese medicine professor Zhang Boli, tianjin university of Chinese medicine and Beijing Wan Gong pharmaceutical industry together to create the transformation of the country's first research and development of traditional Chinese medicine for external use base - tianjin traditional Chinese medicine for external use technology engineering center, gathered up the domestic first-class traditional medicine, clinical medicine, Chinese medicine pharmaceutical engineering, pharmacy, cell and molecular biology, such as multi-disciplinary experts, with national industry development of traditional Chinese medicine and traditional Chinese medicine (TCM) modernization strategy as the guidance, Beijing Wan Gong ointment depth development as the core, carrying out a research into several series of traditional Chinese medicine for external use. Member of Zhang Boli engineering center, director of the technical committee.
The center aims to play a basic scientific research in colleges and universities, talent advantage, in view of the Chinese medicine industry development and the national strategic needs, integrated research and master the technology for years, Beijing Wan Gong ointment for industrialization development of seriation, and studying the related application and basic research. Wan Gong ointment in Beijing as the carrier, corresponding technology platform construction, technical progress and development in related industries. At the same time, by combining study, system development, the promotion of science and technology Beijing Wan Gong ointment content, promote Beijing Wan Gong ointment and internationalization of traditional Chinese medicine for external use.
The herbal medicine for external use technology engineering center, is China's first research and development of traditional Chinese medicine for external use base, is the first and the only for external use of Chinese medicine research and development base, is created by the enterprise in our country the first platform of traditional Chinese medicine modernization of traditional Chinese medicines for external use. It is not only the profound study on the traditional Chinese medicine for external use, but also play a role of traditional Chinese medicine for external use advantage, in turn, open the key to science of traditional Chinese medicine internationalization, at the same time open the "jing Wan Gong" road to lead into the internationalization of Chinese traditional medicine.
Committed to sugar foot
Boosting Chinese medicine go global
Diabetes for the domestic and foreign common metabolic disease, duration of diabetes among 40% of more than ten years there will be risk of diabetic foot. Diabetic foot ulcer is the important reason for diabetic patients disability to death, is the leading cause of non traumatic amputation in many countries. Population survey tip: diabetic foot lower limb ulcer of the cumulative incidence of 3% a year. 20% of foot ulcer patients eventually forced to amputation, the survival rate is lower than non-diabetic amputees, and amputation after 5 years the probability of the contralateral limb amputation was 50%. Diabetic foot patients with chronic difficult to heal wounds of the body surface represented presents the increasing trend year by year, it has complex condition, treatment difficulties, serious to take up health care and social resources, etc, poses a great burden to patients and society. At present, both at home and abroad has not been for the special treatment of the disease. Now more and more people pay attention to traditional Chinese medicine on the treatment of diabetic foot, external use of Chinese medicine treating diabetic foot has a huge domestic and international market demand.
By collecting Chinese medicine for external use to treat cases of diabetic foot, engineering center researchers surprised to find that, some domestic hospital in the treatment of diabetic foot, existing Wan Gong ointment topical use Beijing as soon as possible.
So, general manager of Beijing Wan Gong pharmaceutical Liu Wenwei to look to the field of traditional Chinese medicine for external use "blue ocean", put forward the Wan Gong ointment in the treatment of diabetic foot function expansion in Beijing. In 2009, under the guidance of Zhang Boli academicians, Beijing Wan Gong pharmaceutical industry of tianjin traditional Chinese medicine for external use technology engineering center, researchers quickly Wan Gong ointment in the treatment of diabetic foot was carried out by Beijing pharmacodynamics and evidence-based medical research.
In simulation of human diabetes model animals, the neurodegenerative diabetes foot, burn diabetes foot etc. The effect of three kinds of diabetes foot and mechanism research. Research shows that: "Beijing Wan Gong" ointment for fourteen days later, the rat model with diabetic foot lesion basic healing. Preliminary confirmed from the basic research Beijing Wan Gong ointment in the treatment of diabetic foot efficacy.
And then since 2012, 2 years, by the traumatology branch of Chinese medical association, the national alliance of wound repair specialist as a technical support unit, led by FuXiaoBing academician of Chinese academy of engineering, the Chinese people's liberation army general hospital and all the wound healing and tissue regeneration key laboratory is responsible for basic research, by the people's liberation army 306 hospital army center of diagnosis and treatment of diabetes Xu Zhangrong led by professor, ruijin hospital, Shanghai jiaotong university, west China hospital of sichuan university, zhejiang university school of medicine, second affiliated hospital, sun yat-sen memorial hospital, sun yat-sen university, the fourth affiliated hospital of Harbin medical university, Peking University first hospital jointly participate in clinical research, such as a hospital in the Beijing Wan Gong ointment in the treatment of diabetic foot validation studies.
On February 27, 2014, Beijing JieTiHui Wan Gong ointment treatment of diabetic foot clinical research project was held in tianjin, FuXiaoBing academician of Chinese academy of engineering led the national league for wound repair specialist involved in the project more than ten hospital experts attended the meeting. Meeting, Dr Total project executor Jiang Yufeng Wan Gong ointment on behalf of the Beijing research team, the league of the wound repair and trauma branch of Chinese medical association, made Beijing Wan Gong ointment treatment of diabetic foot wound curative effect evaluation project of the concluding reports: the randomized, multicenter, parallel-group standard treatment evaluation Beijing Wan Gong ointment for the treatment of chronic diabetic foot ulcers in clinical research. According to the report, Beijing Wan Gong ointment for the treatment of chronic wound repair process, proper interpretation of traditional Chinese medicine for external use "simmer pus raw muscle" mechanism, but also with modern medical theory and method to explain the best annotation of ancient medicine. The study confirmed that the Beijing Wan Gong ointment to improve the quality of diabetic foot wound healing has significant role in promoting, simmer pus, further expounds the Chinese traditional medicine science and effectiveness of the treatment, the production of Using modern evidence-based medicine method proved that traditional Chinese medicine for external use only Beijing Wan Gong ointment in treatment of painless the curative effect of diabetic foot wound reliability; It provides theoretical supports for the internationalization of traditional Chinese medicine for external use only, for the development of other similar studies and research provides a good example.
Beijing Wan Gong ointment in the treatment of diabetic foot research, based on modern medical and scientific research mode of scientific conclusions, for its application in the treatment of chronic diabetic foot ulcers provides evidence to support. Wan Gong ointment clinical research project "Beijing", is not only Beijing Wan Gong pharmaceutical digging their own advantages, in turn, seek progress and development, it is a to promote China's traditional Chinese medicine for external use good opportunity towards the international market. Beijing Wan Gong ointment in the treatment of diabetic foot on the remarkable curative effect and unique advantage, examples of the Chinese medicine treatment of difficult disease is unique in the world, will cause the extensive concern of experts around the world.
Chinese medicine external treatment is one of the features of TCM therapy, based on natural medicines, in the skin, bore, acupoints and local lesion, curative effect is small relative to the western medicine has side effects, and the advantage of low prices, for the thriving of the Chinese nation has made immortal contributions. Based on establishing some Chinese medicine for external use and safety control, curative effect is obvious and easily accepted by patients with special advantage, Zhang Boli academician has repeatedly stressed: "traditional Chinese medicine for external use have take the lead in a precondition to the world!" He earnestly Liu Wenwei Wan Gong pharmaceutical general manager of Beijing said: "acupuncture lead implements the internationalization of traditional Chinese medicine," Beijing Wan Gong "series of external use medicine should hopefully lead Chinese medicine to world."
Wan Gong pharmaceutical and Beijing over the past few years, has been committed to Beijing Wan Gong ointment in the treatment of diabetic foot research, is to a traditional Chinese medicine with wings to fly to the world, to study the traditional Chinese medicine for external use and modernization as the breakthrough point, confirm good method of traditional Chinese medicine for external use to treat the world difficult disease, open the Chinese medicine for external use lead breakthrough for the development of internationalization of Chinese medicine, in show the motherland traditional Chinese medicine culture and Beijing Wan Gong charm at the same time, become a booster the pioneer of Chinese medicine internationalization.
The CPPCC national committee Liu Wenwei 2014 CPPCC proposal
- in traditional Chinese medicine for external use, for leading, proposed to speed up the pace of internationalization of traditional Chinese medicine
A, the internationalization of Chinese medicine are faced with the problem
"National medium and long-term science and technology development plan outline (2006-2020)" explicitly pointed out that in the future development of Chinese medicine, priority inheritance and innovation of traditional Chinese medicine development, and puts forward the development of modern Chinese medicine research, development and manufacturing technology, the effective protection and rational utilization of resources, strengthen the protection of intellectual property of traditional Chinese medicine research and international cooperation platform construction."
However, over the years, the internationalization of China's traditional Chinese medicine (TCM) has been no breakthrough. Although many domestic drug firms made exploration in many ways, also have sprung up like "particles" apricot spirit "compound danshen dropping pill" and other individual varieties to enter clinical trials by the FDA hearing cases, taken the first step for traditional Chinese medicine to enter the international market, but from around the world to the safety and efficacy of traditional Chinese medicine, to really go out and outlook is not optimistic. In the clinical research of traditional Chinese medicines in our country, nonrandomized case reports and small sample clinical case summary research majority, the curative effect of this study can not be universal. And most internal and traditional Chinese medicine treatment of disease to the lack of comparative advantage compared with western medicine. Therefore, the lack of outstanding advantage "is the biggest barrier to Chinese medicine internationalization.
Second, in traditional Chinese medicine for external use, for leading, speed up the internationalization of traditional Chinese medicine (TCM) pace
As with acupuncture and moxibustion technology as a breakthrough leading the internationalization of traditional Chinese medicine, Chinese medicine for external use will be leading the breakthrough of internationalization of traditional Chinese medicine.
First of all, the surgical field exist in west medicine is difficult to conquer the world difficult problem, the problem of one of the most representative is chronic wound area. The field including diabetic foot, pressure sores, lower limb vein ulcer and wound infection, etc. At present, the western medicine for the treatment of wounds just stay on the debridement and the use of surgical dressings, clinical curative effect is very limited.
Chronic difficult wound treatment in our country, however, "area" the experience of disease, since there is a record of the zhou dynasty is of more than 5000 years ago. The zhou dynasty set up in the medical administration "sores healing" is a surgeon. In 1604, the Ming dynasty surgical doctor ShenDou walls in its by the surgical kai xuan, ulcers, appropriate plasters theory "in the first proposed the" simmer pus, the production method ", early in the British zoologist "wet healing theory" put forward by the 358. In essence, "simmer pus raw muscle theory" and "wet healing theory" are all show that the growth of the wound, need for wet environment. But "simmer pus raw muscle theory" emphasizes the concept of active repair, through the local microenvironment, actively improve a week in order to achieve the purpose of effectively promote healing, its theory is obviously superior to wet healing theory. Surgery of traditional Chinese medicine (TCM) in simmer pus, under the guidance of the theory, the production of various subject that spawned many classic generic versions, such as Beijing Wan Gong ointment, rubber raw muscle cream, huanglian jiedu paste, raw powder, etc.
In addition, the clinical curative effect in the field of surgical intuitive, less noise, easy to evaluate. Therefore, traditional Chinese medicine for external use in clinical treatment of significant advantages, will become the breakthrough of internationalization of traditional Chinese medicine.
Third, how to upgrade of internationalization of traditional Chinese medicine for external use first
1. To establish a system research, increase policy support from the government level.
Life science with the help of the people's liberation army general hospital dean FuXiaoBing academicians and the member of the people's liberation army third military medical university institute of field surgery vino dc.the influence such as high-end specialist academic advantage, select the typical classic generic, to carry out the international standard of clinical randomized controlled trial (RCT) and "simmer pus raw muscle method" the level of cell and molecular mechanism research, summed up clear evidence of evidence-based medicine, at the same time in the study of side effects. Support related international published papers, strive for entering the international guidelines as soon as possible.
2. Encourage enterprises to establish a national Chinese medicine for external use engineering center, increase policy support for traditional Chinese medicine for external use engineering centers.
In the enterprises having conditions of establishing a national Chinese medicine for external use research and development base, and to give policy support, encourage enterprises to implement the strategy of traditional Chinese medicine for external use of production-study-research cooperation. Through production, strategic cooperation, encourage enterprises to develop extensive science and research and development institutions sharing platform, Shared facilities and test base cooperation, promote the development of traditional Chinese medicine for external use export enterprises.
3. Popularize the use of traditional Chinese medicine for external use in its many forms of knowledge.
At present, the traditional Chinese medicine for external use in medical clinical utilization rate is low. Therefore, through various forms to carry out the traditional Chinese medicine for external use research of using the method, in order to better promote the applications of surface chronic difficult wound diseases. Curative effect for some outstanding classical Chinese medicine for external use products, as soon as possible into the state's surface guide of diagnosis and treatment of chronic difficult to heal wounds, to promote the standardization of clinical diagnosis and treatment to use, external use internationalization to lay a better foundation for traditional Chinese medicine.
This edition are Beijing Wan Gong pharmaceutical information pictures