Traditional Chinese medicine (TCM) antidepressant with evaluation system 
 
 
The 2014-12-31 if then 
 

 
Source: benxi daily 

    With "three technical system, an integrated platform to support the antidepressant medicine, a comprehensive evaluation system through screening of comparative study, first discovered medicinal indianmulberry root, non-toxic cottonseed and traditional Chinese medicine and its active ingredients such as small bushing soup good antidepressant activity
 
    Development of antidepressant TCM with scientific basis. Recently, the Chinese people's liberation army military academy of medical sciences institute of toxic drugs such as Sean lee responsible for completing the "antidepressant application and the establishment of the comprehensive evaluation system of Chinese medicine" project was awarded the first prize for science and technology prize of China association of Chinese medicine in 2014.
 
    Depression belongs to the category of "depression and modern disease" of traditional Chinese medicine, is one of the highest rates of mental illness, has become a serious global public health problem and outstanding social problems. Sean lee said, combining the theory of traditional Chinese medicine, biological and chemical analytic antidepressant effects of traditional Chinese medicine, research and development of safe and effective antidepressant modern traditional Chinese medicine (TCM), is the important direction of new drug research and development in our country. However, due to the lack of evaluation system, perfecting the system in traditional Chinese medicine (TCM) play a role of antidepressant chemicals basis is unknown, its the neurobiological mechanisms of antidepressant regulation is hard to parse, thus severely limit the new drug research and development process.
 
    Home in the early 1990 s, the late famous neuropsychopharmacology ROM qualitative advocated established the first domestic brand to antidepressants behavior evaluation system, and the Chinese people's liberation army military academy of medical sciences institute of toxic drugs zhao ym, cui cb plants and other well-known chemist cooperation created the antidepressant of modern Chinese medicine research, and illustrates the medicinal indianmulberry root, small bushing soup and non-toxic cottonseed neurobiology effect of traditional Chinese medicine (TCM), regulation mechanism and chemical base, and successfully developed the first antidepressant five types of Chinese herbal medicine medicinal indianmulberry root oligosaccharide capsule, and sum up Chinese medicine antidepressant effect mechanism, to form the perfect feasible antidepressant medicine evaluation system and strategy.
 
    In order to further improve the development of the modern Chinese medicine research of depression, over the years, Sean lee and his research team combined with multiple targets of traditional Chinese medicine syndrome and the characteristics of the overall adjustment, created the specifications advanced antidepressant medicine research "behavioral neurobiology - plant chemical multi-level evaluation technology system research" and "model behavior pharmacological evaluation platform", namely "the three technical system, an integrated platform of antidepressant medicine comprehensive evaluation system. The system looks at how overall system adjustment, pay attention to between disciplines closely cooperation with repeatedly, can quickly find and evaluate antidepressant Chinese native medicine ingredient system. At present, the system has been incorporated into Beijing municipal key laboratory and state key laboratory.
 
    In the process of the treatment of depression, compared with western medicine of traditional Chinese medicine has a unique advantage and potential. Traditional Chinese medicine because of its composition effect and system adjustment, the characteristics of multiple target action, at the same time of effective treatment of depression, has the advantages of low toxicity, easy tolerance. A large number of studies have shown that tonic kind of traditional Chinese medicine through the body's nervous, immune, endocrine system network more overall adjustment, have a role for the treatment of nerve mental illness. R&d team through the system to screen for the first time found that medicinal indianmulberry root, non-toxic cottonseed and traditional Chinese medicine and its active ingredients such as small bushing soup good antidepressant activity.
 
    Based on traditional Chinese medicine overall adjustment, from the monoamine systems, neural plasticity, neuroendocrine and immune regulation, such as multiple layers, the team first expounds the Chinese medicine science antidepressant common nervous, immune, endocrine network control rule, is presented based on the system to adjust the vicious cycle of "two stage" of new mechanism and its technical system, and successfully applied to antidepressant found and function mechanism of traditional Chinese medicine research.
 
    So far, the study received two national new drug certificate, China 12 invention patents, the United States 1 invention patents, take the lead in establishing the antidepressant effect of traditional Chinese medicine, multi-level comprehensive evaluation system systematically clarified the multiple herbal antidepressant effects of neurobiology regulation law and chemical base, successfully developed the first modern sense of antidepressant medicine, put forward a new and pathogenesis of depression occur and its technical system, formed the multidisciplinary cooperation, multiple model evaluation, multi-dimensional analysis, multi-level research development strategy, provides scientific basis for the development of antidepressant Chinese traditional medicine, and provides the beneficial reference for the research of TCM modernization.