Theory of medicinal material moisture content and the dose conversion 
 
 
Xu Lipeng MuLanCheng Guo Yun Tong xiaoLin China academy of traditional Chinese medicine hospital of the gate 
 
 
China's traditional Chinese medicine to 

    The primitive dose after modern textual research, has been confirmed in treatise on febrile disease, 1 two is equal to the modern 13.8 grams, one thousand mystery seems to have resolved. But the choice by the parties by this conversion standard doses, is still hard to avoid.
 
    Such as large bearing gas soup, the dose of rhubarb for four two, according to former convert standard dose of 55.2 grams, and clinical application of big bearing gas soup in treatment of acute intestinal obstruction with 10 ~ 30 grams can achieve satisfactory curative effect. And like a small bupleurum decoction, pinellia dosage for half a litre, in accordance with the typhoid proposed by the famous professor Hao Wanshan conversion standards, the dose of about 50 ~ 60 grams, this has to do with the stipulation of "pharmacopoeia of China 3 ~ 9 grams of dosage range. Therefore conversion standard is still difficult to reference as the dosage of clinical prescription.
 
    The author through to the treatise on febrile disease of traditional Chinese medicine prescriptions contained processing method, boiling, and custom in ancient literature analysis, put forward a kind of the key factors that affect the party dose conversion - medicinal material moisture content, to explain the huge differences of the ancient and modern dose, we have mentioned as below.
 
    The ancient custom is different
 
    Dose of traditional Chinese medicines are used in modern prescription refers to be carried out in accordance with the prescription of weighing, after processing the slices of weight. Prescription in the annotation of "main" or "fire" and so on footnote, before all means yinpian prescription, crude drugs needed for processing method. In short, in the modern Chinese medicine prescription medicine is created first, after weighing. Prescriptions of northern and southern dynasties Chen Yanzhi by "above the old party drug law" of a roll, and the title suggests, the Chen Yanzhi of northern and southern dynasties, and medicine method have changed compared with before, so called "old party drug law". Sun simiao in tang dynasty by the daughter s, also clearly put forward "all pills for choosing cook mortar specimen, and then balance with use, shall not be life balance", that means from the northern and southern dynasties to early tang dynasty, the medicinal materials measurement method is more chaotic, so sun-style special emphasis on medication must first after processing and measurement. Chen, sun two account of the acknowledgement from the side tip the generation before the acknowledgement - a different current custom measurement, before they are created.
 
    Difference is the key to the ancient custom medicinal material moisture content difference. The following processing methods in treatise on febrile disease and the influence of the resources of medicinal material moisture content be analysed one by one.
 
    main
 
    Magnolia bark must be more in the treatise on febrile disease "main". Code is necessary in a really big bearing gas soup "barbecue make yellow". Zhongjing contemporaries and xu shen's said wen jie zi "cloud:" main, meat, the meat on the fire ". So in the treatise on febrile disease "main" refers to the fire. After burning, the medicine will significantly reduce the water content of the above. Especially the "main make yellow" qiqi tushuo acid-insoluble ash, suggested that before the code is the "main" is blue, more fresh acid-insoluble ash, its high water content.
 
    The gun
 
    Said wen jie zi "cloud:" hair gun, grilled meat, "barbecue is not peeling. Aconite root in treatise on febrile disease in addition to the born with, are to be "gun, peeled and break eight piece". "Huang notes for later generations historical records about" lateral "processing method has been clear about the treatise on febrile disease" gun "method of lateral root of aconite: will bright stove, lateral root of aconite and soot from a furnace heated to a little crack, and then cut to be burned black, break into eight pieces. Can "break eight piece" prompt, gun after soft, free cutting lateral root of aconite, water more.
 
    boil
 
    In treatise on febrile disease "endure" word, said wen jie zi "explanation:" boil, dry Fried ", refers to the drug in tiles, baked-on method to fire. The author in September 2014 to hometown of nanyang zhongjing field catch article 30 live leeches, wet weight of 72.5 g. As above method "endure", after dry weight reduced to 14.6 grams, the moisture content of the live leeches up to about 80%.
 
    wash
 
    Pinellia tuber in the small bupleurum soup, soup of this decoction heart of processing method must be "wash". "Huang notes recorded the method of" wash "pinellia tuber, and said" with size break to fritter, is said to into the soup; if paste wine pills, all must be exposed dry is called the ", the tips into one pinellia after soaking peel was not used for drying, but direct slicing into one.
 
    peel
 
    Cassia twig decoction of cinnamon (according to textual research,, true LiuCheng cassia twig should be "cinnamon"), large bearing gas soup of magnolia officinalis were "peel". "Peel" condition is the premise of the bark gets higher water content, otherwise will not remove after completely dry.
 
    Rhubarb in artemisia capillaris soup also need to grubbing skin. The author respectively to dry fresh rhubarb and rhubarb peel test, the former can be easily stripped skin, while the latter after exposure to dry couldn't peel them.
 
 
 
Unfinished, full text links: http://www.cntcmvideo.com/zgzyyb/html/2015-06/12/content_100146.htm