Tonifying spleen kidney method is effective to treat myasthenia gravis

Time: 2015-11-20

Source: China's traditional Chinese medicine

The author: butyl

Report from our correspondent (reporter ding ocean) recently, the study by the university of liaoning traditional Chinese medicine "tonifying spleen kidney method for the treatment of myasthenia gravis clinical curative effect evaluation" project has been proved that by the method of tonifying spleen kidney for the treatment, and the fitting with tonifying spleen kidney effect of astragalus membranaceus compound particles used for clinical purposes, can effectively improve Ⅰ, Ⅱ type myasthenia gravis symptoms. At present, the treatment has thousands of patients with myasthenia gravis, obtain good effect, in which hundreds of cases has been completely stopped and back into the work. The results of the study are scientific evaluation method of tonifying spleen kidney treatment the clinical curative effect of Ⅰ, Ⅱ type myasthenia gravis.

Myasthenia gravis is an autoimmune disease characterized by drooping eyelids, construct the sound, chew, swallow, difficulty breathing and shaft neck, is "the morning light both heavy" phenomenon, serious cause breathing palsy life-threatening (myasthenia crisis), the recurrence rate is high. Current application of the thymus gland surgery or radiation therapy, hormone and immune inhibitor treatment, have been found effective and less side effects of therapy for a long time.

The group professor jing-sheng zhang, spleen and kidney damage is present throughout the basic pathogenesis of myasthenia gravis course, replenishing spleen kidney is the basic treatment of the disease, and from a tonifying spleen kidney effect of astragalus membranaceus compound particles used for clinical purposes. Research through the observation of T cell subgroup, proteomics, nerve muscle ultrastructure, electromyogram index changed, for the first time to explore the pathogenesis of the disease from the point of view of proteomics, reveal tonifying spleen kidney is a the mechanism of action of astragalus membranaceus compound particles and the pathogenesis of the disease. In the national "11th five-year plan" major project of knotty, through a randomized, double-blind, multicenter, placebo-controlled clinical trial, the curative effect evaluation standard of modern medicine, but also can reflect curative effect to improve the curative effect of using more evaluation questionnaire, scientific evaluation method of tonifying spleen kidney Ⅰ treatment, the clinical curative effect of Ⅱ type myasthenia gravis.

Research results showed that astragalus membranaceus compound particles can effectively improve Ⅰ, Ⅱ type myasthenia gravis symptoms, have promote nerve muscle joint postsynaptic membrane repair, work time is 4 weeks, the eye muscle and chewing dysphagia, and reduce the serum concentration of acetylcholine receptor antibody, treatment group effective rate was 78.51%, no serious adverse reaction, obvious side effects, and liver and kidney damage.

The results of the study was awarded first prize of China council for the promotion of traditional Chinese medicine research the progress of science and technology, liaoning provincial government science and technology progress award.