Address: Beijing's xizhimen south street, xicheng district
The British garden 1 floor. Room 824
Zip code: 100035
Telephone: 010-58562339
Fax: 010-58562339
Email address: cngjzj@163.com
Web site (click on the url link directly left) :
http://www.cngjzj.com/
Blog (click on the url link directly left) :
http://blog.sina.com.Cn/CNGJZJ
To xizhimen south street, xicheng district building to the British garden route
L airport line 1
Take the airport shuttle from the airport, the dongzhimen station transfer to metro line 2 to xizhimen direction and get off at xizhimen station, from C outbound, go straight to the east 100 meters on the right side to xizhimen south street, north to walk to the t-junction namely to the British garden 1 floor downstairs.
L airport line 2
From the capital airport take airport bus to xidan, get off at no.22, take a taxi to xizhimen south street English garden 1 floor.
L bus subway near:
106 bus GuanYuan: 107 road, express way
Bus: xizhimen south road 387, 44 road, inner ring 800, 816 road, inner ring 820, 845 road
Che zhuang: subway line two
Xizhimen subway: metro line 2
Buses and attempts: 107 road, 118 road, 701 road
Buses and north zhuang: 209 road, 375 road, 392 road
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2016年06月02日
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Chinese scientists decode the village card virus structure Is expected to develop specific
Release date: 2016-05-25
Source: the future network
Author: JinYing
The reporter learns 25, college of life science professor hai-tao Yang led the research team resolve the village card virus helicase 1.8 (el) high resolution crystal structure, is expected to develop a drug for the treatment of village card virus.
Village card heat is caused by the village card virus, a mosquito-borne infectious diseases, symptoms similar to those of dengue fever, including fever, rash, headache, joint pain, muscle pain, and the purulent conjunctivitis, etc. There is evidence that village card virus infection with fetal and neonatal microcephaly and some serious neurological complications. In February this year, the world health organization declared village card virus a "public health emergency of international concern", 33 countries reported village card the spread of the virus. However, there are no vaccine for this virus infection and effective treatments.
Helicase is one of the important targets for design of antiviral drugs. In the process of virus proliferation, helicase for almost all the necessary to viral replication proteins. Virus helicase and village card can get energy through hydrolysis nucleoside triphosphate, loose the virus nucleic acid chain. This is the village card is a basic steps to viral replication.
, the researchers said the village card virus specific activity sites as the key target helicase, is expected to stop viral replication and to prevent the virus infection, and for the development of inhibiting viral replication and control village card virus infected antiretroviral inhibitors laid the foundation.
According to introducing, hai-tao Yang team resolved village card virus helicase crystal structure, resolution of 1.8 (el). The high resolution structure reveals the key areas of nucleoside triphosphate hydrolysis, and accommodate RNA positive charge of the channel, for the village card virus drugs research and development to provide an accurate model. The findings, published online yesterday in the journal.
