Beside the disappear of traditional Chinese medicine (94) in addition to the expansion of semen raphani

Modern research

Main ingredients

Fatty oil, volatile oil, volatile oil with Methyl mercaptan (Methyl mercaptan), etc. More content in fatty oil Erucic acid, Erucic acid), linoleic acid, linolenic acid, sinapic acid glyceride (Glycerol sinapate). It is containing radish element (Raphanin). The separation to beta Sitosterol (beta Sitosterol)

Pharmacological effects

1. The experiment showed that the function of gastrointestinal movement of raw products of semen raphani, and Fried, grilled processed products can increase in vitro rabbit intestinal contraction, but for in vitro rabbit intestinal tension had no obvious effect; Three kinds of products can fight adrenaline inhibition of bowel loops. Raw products of semen raphani can reduce article isolated gastric muscle tension, Fried radish seed and grilled would make its tension after the first rise in lower of semen raphani. Three kinds of products can make gastric muscle contraction amplitude increased; Make gastric pyloric circular muscle tension and increased contraction. Fried radish seed the promoting function of small intestine in mice; Three kinds of preparations are inhibitory effect on gastric emptying in mice.

2. Resistant to the original microbial water infusion of semen raphani (1:3) in vitro of concentricity versicolor bacterium, MAO Xu Lan favus bacteria, Mr Du ang small buds versicolor bacterium, rust color small buds versicolor bacterium, wool, star slave card small buds versicolor bacterium bacterium such as skin fungi have different degrees of inhibition. Radish seed contains antibacterial substances, the effective components in radish. For there was a significant inhibitory effect on staphylococcus aureus and escherichia coli; Also can inhibit streptococcus, rotting aureus, pneumococcus, such as e. coli growth. Radish element to virus inhibition, sensitive for DNA virus is RNA viruses.

3. The antihypertensive effect of water and alcohol extracts of semen raphani to cats and dogs, intravenous, there is a very significant antihypertensive effect; Extract to rabbit gastric lavage and renal hypertension rats, also have significant antihypertensive effect. According to the report, the antihypertensive effect of semen raphani has nothing to do with the sympathetic nerve, a large amount of atropine or cut off on both sides of the vagus nerve can not block the antihypertensive effect of semen raphani, its antihypertensive mechanism and M - choline response is less; Procaine can reduce the decompression range of semen raphani, prompt intravascular receptor may be associated with the pharmacological effects of semen raphani. Experimental results show: the intestinal canal of semen raphani can relax smooth muscle, and increase the dog limb blood flow, explain the role to dilate blood vessels; Vertebral artery dosing of rabbits, cats have antihypertensive effect. So you can think of the drug in addition to blood vessels outside the direct expansion effect caused by the step-down, and can play a role of the step-down partly by the central nervous system. Also have the experiment showed that semen raphani injection on acute hypoxic pulmonary hypertension in rabbits and arterial pressure is significantly lower; Increasing the dose of semen raphani, can make its reduced pulmonary arterial pressure, body strength increase, compared with phentolamine, can obviously prolong decompression of semen raphani.

4. Other function in the rat feeding extract of semen raphani for a long time, the synthesis of thyroid hormone can interfere with it. By intraperitoneal injection of water extract of semen raphani to rats, the croton oil granulomatous inflammatory hyperplasia have obvious inhibitory effect, but with weak permeability. By in separation of semen raphani beta sitosterol have antitussive and expectorant effect, provides the credible theoretical basis for the treatment of chronic bronchitis of semen raphani. The composition is to treat human serum cholesterol, prevent coronary atherosclerosis, tip may also have a certain role in the treatment of coronary heart disease (CHD).

The compatibility of utility

Compatibility of semen raphani ginseng: the gas xiaoshi of semen raphani; Ginseng tonifying qi spleen. Both wu played by a total of tonifying qi of the spleen and the gas xiaoshi efficacy Used in the treatment of spleen and stomach weak due to the lack of power, stay, often abdominal distension full, etc.

Physical medicine (drug)

Radish pigment with mild toxicity in mice and in vitro frog heart. Aqueous extract in mice abdominal cavity injection of the median lethal dose of 127.4 g/kg (123.8 137.1), more animals than dosing l hours convulsions and death. Rats lavage daily 100, 200 and 400 g/kg, for 3 weeks, the blood picture, liver and kidney function and main organs are not seen.

- clinical application of semen raphani

Semen raphani

1, to treat senile constipation: elderly constipation, similar to "spleen about" in treatise on febrile disease. "About" spleen is spleen weak unable to stomach line its fluid, so the number of urine was difficult. Recurrent constipation frequency in recent years, the writer take Fried radish seed porphyrization 15 g, in the boiling water a blunt after a meal, "turn to disappear of gas, gas does not hurt, because its can go on diet, gas points complacent its breed" (see "recorded in medical applications and the west"). More persistent, stomach Yin and dregs, benefit a lot. In clinical to Chen, stagnant to purge the, also not constrained by "cold, warm, embellish, attack and" four solution, in the add Fried radish seed, have more effect.

2, fry with phlegm asthma: neijing cloud: "in the stomach, in about lung." Na, transport, ascending and descending disorder of spleen and stomach, eating gathered in the stomach and phlegm dampness. And lung phlegm, each by the lung by evil, interpromotion loss caused by department. With semen raphani xiaoshi phlegm, qi anti-asthma, keep warehouse is very muddy, and this also. With semen raphani, phlegm are broken down; No phlegm, regulating spleen and stomach qi activity, lifting and evil difficult to save.

3, use agent spit saliva: Fried radish seed, down than up; Born with, is up more than drop, can spit saliva. Compendium of material medica "this product set son born with" water research, vomit wind phlegm ". Such as cough phlegm salivary indicates sheng, or because of phlegm turbidity MengQing know-how and heavy head dizzy, all usable raw research at the end of the adjustable gear, 30 g of semen raphani agent to vomit, is an evil. Application of vomiting method, however, must be physical Sundays, upright, appropriate of the failure has a [3].

Traditional Chinese medicine (TCM) properties

Summary of medicinal materials

Traits of seeds ovoid or oblong, slightly compressed, 2.5 ~ 4 mm long, 2 ~ 3 mm wide. Surface yellow brown, reddish brown or gray brown, dark brown round hilum at one end, side several longitudinal groove. Seed thin and brittle, cotyledons 2, yellowish-white, oily. Light, slightly bitter, bitter.

Chemical composition containing volatile oil and fat oil, volatile oil contains alpha, beta has olefine aldehyde and beta, gamma - have enol, etc; Fatty oil contains high erucic acid, erucic acid), linoleic acid, linolenic acid and erucic acid glyceride, etc.; Still containing radish element (raphanin), movement of glucoside.

Sexual flavour: flat, sheen, gansu.

Through: for the lung, spleen, stomach.

Functional indications: xiaoshi in addition to the bulge, gas phlegm reduction. Used for food stagnation, often abdominal distension, pain, constipation, stagnant, diarrhea, phlegm indicates wheezing cough. Into the spleen, stomach, lung, can disappear in addition to the bulge, efficacy significantly, there are "blunt wall wall," said. Conventional clinical to treat solid (food, wet, stagnant) certificate. , however, the goods is not simply disappear in addition to the bulge, the deficiency syndrome of, effect is better, because of their sexual peace, its smell and is not completed, unbiased prevail, not constrained by "the blunt wall wall", at the risk of broken gas (more than) are actually flat gas, abandoned in the and.

Usage and dosage: decoction, 6-10 g with vomit wind phlegm, fry with gas under the disappear of phlegm.

Use note: the goods scattered gas consumption, so the deficit without food retention, phlegm stagnation is careful. Should not be Shared with ginseng.

Processing method: 1, radish seed: take the original medicinal herbs, to remove impurities, rinse and dry. When dolly.

2, Fried radish seed: net semen raphani, buy container preheating making, heat the mixture gently, to summon up, crackle, appearance, color yellow inside, and escape of fragrance, remove to cool. When dolly.

Processing function: 1, radish seed: gan, xin, sexual flat. Lung, spleen, stomach. Xiaoshi in addition to the bulge, the effect of gas phlegm reduction. Can produce bulk of semen raphani, longer than wind chung spit sputum. For the goods at the end of the warm clothing, can promote vomiting wind phlegm.

2, Fried radish seed: Fried after sex, medicinal detente, have fragrance, can avoid the side effects of nausea after promotional clothing, and longer than the food in addition to the bulge, lower gas phlegm. Often used for dyspepsia diarrhea, asthma cough. Easy to crush after Fried crispy texture at the same time, and the solution.

Product description: 1, radish seed: a kind of ovoid or oblong, slightly compressed. On the surface of yellow brown, reddish brown or beige. Hard seeds yellow-white, broken after oil. Taste slightly bitter.

2, Fried radish seed, radish seed, colour and lustre is deepening, very brittle, yellow inside, has a fragrance.

Raw medicinal materials identification

Character identification: dry seeds oval or nearly ovoid, slightly compressed, ca. 3 mm long, 2.5 mm wide. Several longitudinal surface red-brown, side ditch, end the navel, brownish round dot swelled. Use a magnifying glass to observe, all are dense reticulate. Visible qualitative hard, after the break with yellowish-white or yellow seeds, there are oily. Odourless, taste sweet, slightly bitter. It is beautiful thick and full, oily concurrently.

Microscopic identification: powder: yellow brown.

1. The seed coat palisade cells light yellow, orange, or yellow brown. Section view cell 1 column, general 10-37 mu m radial, tangential 7-12 microns, the outer wall and lateral wall of the upper thin, most of wall and wall thickening, sidewall central YouHou; Long view class polygon or polygonal surface, wall thickness 2-4 microns, intercellular layer of very fine.

2. Kind of subcutaneous skin cells form, the section view flat oblong, outer wall and sidewall shrinkage, cell line is not clear, which the palisade cells. In addition, the endosperm cells, cotyledon cells; Kind of skin epidermal cells and liquefied observation is not clear.

The pharmacological efficacy

1. The disease resistance of original microbial action:

Aqueous extract of semen raphani on staphylococcus aureus and escherichia coli has significant inhibitory effect, such as water infusion of concentricity versicolor bacterium, MAO Xu Lanshi favus bacteria, Mr Du ang microspore bacteria, rust color small spore tinea versicolor bacterium, wool small spores in bacteria and star slave cartesian bacteria have different degrees of inhibition. Radish (1 mg/ml concentration in vitro has obvious inhibitory effect to a variety of bacteria, on staphylococcus aureus, shigella, salmonella typhi and the MIC of escherichia coli, respectively for 40, 125, 125 and 200 MCG/ml.

2. Detoxification:

Radish pigment in vitro and bacterial toxins detoxification significantly mixed management, dilution of 1:20 0 can neutralize 5 a lethal dose of tetanus toxin, 1:500 neutralizes the 4 a lethal dose of diphtheria toxin, diluted to 1:16 00 fashion can reduce the skin necrosis of diphtheria toxin.

3. The antihypertensive effect:

Aqueous extract of semen raphani has obvious antihypertensive effect, rabbits, cats and dogs for anesthesia, intravenous when all can cause animal blood pressure to drop. Research for the influence of rabbit acute hypoxic pulmonary hypertension of semen raphani results show that the injection of semen raphani (1 ml rather crude drug 1 g) 0.3 1.2 ml/kg dose intravenous, can significantly reduce the experimental pulmonary hypertension, and significantly lower arterial pressure. Reduced pulmonary arterial pressure, body strength of semen raphani and phentolamine basic equal. Increasing the dose of semen raphani has failed to make the reduced pulmonary arterial pressure, body strength increase, only to extend the time of decompression, extended than phenol torah clearly show. Adopting continuous trace caused by intravenous injection can inhibit acute hypoxia pulmonary hypertension, at the same time reduce the reduce the side effects of arterial pressure.

4. Effects on cardiac hemodynamics:

4.1. The impact on the arterial pressure and heart rate: injection of semen raphani (1 ml rather crude drug 1 g) by 1.0 ml/kg intravenous anesthesia dog, can make the body of the artery systolic blood pressure (SAP), diastolic blood pressure (DAP), average arterial pressure (MAP), respectively 10.9, 13.9, 15.2 mmHg, pulmonary artery systolic pressure (SPAP), pulmonary artery diastolic pressure (DAPA), average pulmonary artery pressure (MPAP) lower 4.6, 4.3, 3.9 mmHg, respectively, compared with itself before using this drug has a very significant difference (P < 0.01). No obvious change in heart rate before and after dosing.

, effects on vascular resistance: 4.2 after injection intravenous injection of semen raphani, make body vascular resistance (SVR) and pulmonary vascular resistance (PVR) reduced obviously, SVR from 4583.5 + / - 632.45 to 3976.7 + / - 339.86 dyn. S/cm, PVR from 530.5 + / - 6.821 to 411.8 + / - 80.98 dyn. S/cm, own comparison before and after medication (P < 0.05 and P < 0.01.

4.3. Effects on cardiac hemodynamics: six dogs after intravenous injection of 1.0 mg/kg of semen raphani, cardiac output (CO), cardiac index (CI), stroke output (SV), stroke index (SI) are no obvious changes, before and after medication itself is no statistical significance (P < 0.05). Medication after an abnormal left ventricular index (LVSWI) and pulsation index (RVSWI) significantly reduced the right ventricle, LVSWI before and after medication were 40.12 + / - 2.83 and 33.2 3.88 mm; RVSWI was 5.34 + / - 0.74 and 0.74 + / - 0.52 (P < 0.01, R < 0.05).

Content determination

According to high performance liquid chromatography (appendix Ⅵ D).

Chromatographic conditions and system suitability test with phenyl silane bonded silica gel as the filling agent;

With acetonitrile - 3% glacial acetic acid solution (or 5) as mobile phase; Detection wavelength of 326 nm. Theoretical plate number calculated by sinapine peak should be not less than 5000.

Reference substance solution system be on the waiting list of sinapine thiocyanate control right amount, precision said, brown bottle, add methanol made each 1 ml contains 40 mu g solution, quick.

System be on the waiting list of this product of test sample solution powder (3 screen) is about 0.5 g, precision said, with a plug in the conical flask, precision add 70% methanol 50 ml, plug, said weight, ultrasonic processing (power 250 w, frequency 50 KHZ) 30 minutes, put the cold, again according to weight, make up the weight loss reduction with 70% methanol, shake well, filtration, take the filtrate, brown bottle, quick.

Measurement precision respectively from the reference substance solution and 5 mu l of test sample solution, injection liquid chromatograph, determination, quick.

This article calculated on dry goods, including sinapine with sinapine thiocyanate (C16H24NO SCN), shall not be less than 0.40%.

Function of the attending

Can treat senile constipation

Senile constipation, similar to "spleen about" in treatise on febrile disease. "About" spleen is spleen weak unable to stomach line its fluid, so the number of urine was difficult. Recurrent constipation frequency in recent years, the writer take Fried radish seed porphyrization 15 g, in the boiling water a blunt after a meal, "turn to disappear of gas, gas does not hurt, because its can go on diet, gas points complacent its breed" (see "recorded in medical applications and the west"). More persistent, stomach Yin and dregs, benefit a lot. In clinical to Chen, stagnant to purge the, also not constrained by "cold, warm, embellish, attack and" four solution, in the add Fried radish seed, have more effect.

Fry with phlegm breathe heavily

Neijing cloud: "in the stomach, in about lung." Na, transport, ascending and descending disorder of spleen and stomach, eating gathered in the stomach and phlegm dampness. And lung phlegm, each by the lung by evil, interpromotion loss caused by department. With semen raphani xiaoshi phlegm, qi anti-asthma, keep warehouse is very muddy, and this also. With semen raphani, phlegm are broken down; No phlegm, regulating spleen and stomach qi activity, lifting and evil difficult to save.

Born in spit saliva

Fried radish seed, down more than the rise; Born with, is up more than drop, can spit saliva. Compendium of material medica "set son only born with" water research, vomit wind phlegm ". Such as cough phlegm salivary indicates sheng, or because of phlegm turbidity MengQing know-how and heavy head dizzy, all usable raw research at the end of the adjustable gear, 30 g of semen raphani agent to vomit, is an evil. Application of vomiting method, however, must be physical Sundays, upright, not failure is appropriate.

Semen raphani

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"Chinese pharmacopoeia" : semen raphani

Semen raphani medicine name 】 【

[English] by RAPHANI

"Alias" turnip

【 origin 】 this product is a cruciferous vegetables radish (Raphanus sativus l. dry mature seeds. Summer cutting in the plant when ripe, drying, rub out the seeds, removing impurities, then dry.

【 characteristics 】 this product is class ovoid or oblong, slightly compressed, 2.5 ~ 4 mm long, 2 ~ 3 mm wide. On the surface of yellow brown, reddish brown or gray brown. Dark brown round hilum at one end, side several longitudinal groove. Seed thin and brittle, cotyledons 2, yellowish-white, oily. Odourless, taste light, slightly bitter.

[identify] (1) take a small amount of this product powder, in vitro and sodium hydroxide 1 small grains, buy alcohol lamp on heat, cold, 2 ml of water dissolving, filtration. Take 1 ml filtrate, acidification, and 5% hydrochloric acid solution with hydrogen sulfide produced, meet new system of lead acetate test paper, glossy dark brown.

(2) in sodium cyanide iron nitroso 1 small grain, white porcelain plate, add water 1 ~ 2 drops make dissolved, add [identify] (1) under the rest of the filtrate 1 ~ 2 drops, or purple.

(3) take the product powder 1 g, plus ether 30 ml, heating reflux for 1 hour, leave to ether liquid, liquid to 10 ml after washing and dry, with ether and methanol 20 ml, heating reflux for 1 hour, filtration, the filtrate zhenggan residue with methanol 2 ml to dissolve, as the test solution. Another contrast medicinal materials of semen raphani 1 g, with the legal system into a controlled medicine solution. According to thin layer chromatography (appendix Ⅵ B) test, 5 mu l learned these two solutions, each point in the same silica gel GF254 thin layer plate, with ethyl acetate and formic acid and water (10:2:3) of the upper solution for expansion agent, and taken out, dried, can be examined under a uv lamp (254 nm). In the chromatogram of the test, chromatographic corresponding to the position, show the same color spots; Sprayed with 1% 10% of vanillin sulfuric acid ethanol solution, heating to the spot color is clear, in the chromatogram of the test, chromatographic corresponding to the position, the same color spots.

[up] semen raphani: to remove impurities, rinse and dry. When dolly.

Fried radish seed: net semen raphani, stir-fried method (appendix Ⅱ D) according to summon up. When dolly.

Simba, sexual flavour 】 【 gan, ping.

"To the" to the lung, spleen, stomach.

Xiaoshi function attending 】 【 except expansion, gas phlegm reduction. Used for food stagnation, often bloating pain, constipation, stagnant, diarrhea, phlegm indicates asthmatic cough.

【 usage and dosage 】 4.5 ~ 9 g.

【 storage 】 ventilated, dry place, moth-proofing.

【 from 】 "Chinese pharmacopoeia"

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The Chinese medicine dictionary: semen raphani

Semen raphani medicine name 】 【

"Pinyin" Lai Fu Z ǐ

"Alias" radish (material medica) "set son.

【 origin 】 the Ben yan addendum of righteousness"

【 origin 】 is the seed of crucifer movement. Summer, the autumn mature seeds removed all strains, when dried, rub out the seeds, removing impurities, dry.

"Habitat division" across the country are produced; Agriculture in hebei, henan, zhejiang, heilongjiang, etc.

【 description 】 dry seeds oval or nearly ovoid, slightly compressed, ca. 3 mm long, 2.5 mm wide. Several longitudinal surface red-brown, side ditch, end the navel, brownish round dot swelled. Use a magnifying glass to observe, all are dense reticulate. Visible qualitative hard, after the break with yellowish-white or yellow seeds; Have oily. Odourless, taste sweet, slightly bitter. With big granule, full, oil supplied is preferred.

Seed fatty oil, volatile oil chemical composition 】 【. Volatile oil with methyl mercaptan, etc. Fatty oil contains high erucic acid, linoleic acid, linolenic acid, and mustard acid glyceride, etc. Still contain antimicrobial substances called radish element.

[pharmacological action] (1) the antibacterial effect

Radish seed contains antibacterial substances, the effective components in radish element, in the concentration of 1 mg/ml of e. coli staphylococcus and the secret that is significant inhibitory effect, and can affect all kinds of plant seed germination. After a kind of oil isolated from semen raphani, known as the "Sulforaphen", 1% concentration can be against streptococcus, rotting aureus, pneumococcus, such as e. coli growth. Some people think that this may be the same material

(2) the antifungal effect

Movement of water infusion (1:3) in vitro of concentricity MAO versicolor bacterium of six kinds of skin fungi have different degree of inhibition.

(3) other role

Variant of the extract, long-term feeding rats, can interfere with the synthesis of thyroid hormone

Radish element in mice and in vitro toxicity 】 【 frog heart with mild toxicity.

[up] semen raphani: whisk to impurities, rinse dirt, remove, dried, mash it. Fried radish seed: net semen raphani, set the pot gently to micro, and has the aroma of degrees, remove and let cool.

【 sex flavor 】 XinGan, ping.

Material medica: (1) the south yunnan "of temperature, taste bitter."

(2) "of materia medica" : "XinGan, non-toxic, ping."

(3) "the jade Chinese catalpa medicine solution", "sheen, hot."

(4) "recorded in medical applications and the west" : "born with a little sheen, temper, fry with temperature."

"To the" into the lungs, stomach, through.

Material medica: (1) the south yunnan "into the spleen, lung, 2."

(2) the pharmaceutical chemical righteousness ":" into the spleen and stomach."

(3) "new materia medica" : "into the liver, lungs through."

Under the function of attending 】 【 gas anti-asthma, xiaoshi phlegm. Phlegm cough asthma, food retention and qi stagnation, chest abdominal distention, diarrhea after heavy.

Material medica: (1) the solar corona child ", "water research, spit wind phlegm: vinegar research detumescence poison."

(2) the daily material medica: "jaundice and cure skin yellow like gold, low water hot red."

(3) the material medica south yunnan: "under the wide, letting inflation, phlegm reduction, shout out, intestines and stomach is stagnant, treat a lump in the abdomen, abdominal pain."

(4) "of materia medica", "gas anti-asthma, phlegm, xiaoshi, in addition to the bulge, urine, stop pain, diarrhea after heavy, spots."

(5) "cure a wood code to" : "born with, vomit wind phlegm, wide XiongGe, Joe spots; heat, gas sputum elimination, crucial product, after treatment."

6. "new materia medica", "phlegm in addition to the wind, and sweating."

7 "with interest in eating spectrum", "cure phlegm, asthma, staining gas drum, head wind, drowned, closed and one supplements."

【 usage and dosage 】 oral: decoct soup, 1.5 ~ 3 money; Or the pill, powder. External use: at the end of the study apply.

【 note 】 the debility in clothing.

"Ben from the new" : "the frail clothes, asthma hard cloth."

【 compound 】 (1) on the worth of gas cough, much sputum palpitations, salivary purulent blood: a match of semen raphani, grind, decoct soup, feed on clothing. (" bromides heart mirror)

(2) cure whooping cough: green radish seeds, baked dry, grind fine powder. Sugar water to take a few, a number of the back. (jiangxi traditional Chinese medicine (12) : 1963)

(3) put out of phlegm and promote staining, encounter the taste that: radish for net, steamed, drying of ginger juice soak mung bean big steamed cake balls. Take three pills each to tianjin swallow mouth, day three suits. (Fu Zi medical integration clear gold pill)

(4) full cure cough, sputum reversed flow of qi new: Perilla, white mustard and radish. Wash and small fry, na on the break, in raw silk pouches, boil soup to drink. With the delicacies, generation of sip with tea, unfavorable suffer more. (asaps medicine through the third raise pro soup)

(5) to treat all dyspepsia: ha 6 two, two two divine comedy, pinellia, poria cocos each couple, dried tangerine or orange peel, forsythia, radish each one or two. For at the end of the cook a cake pill as the child. Take seven, eighty balls, each food far, clear soup. (Dan brook method to protect and pill)

6 inflatable gas drum up cure: semen raphani, grind, to filter water juice, leaching sand one or two, one night, Fried dry, leaching and Fried, all seven times, as the late. Per meter YinFu a money. (" chu set check health providers ")

All landowners have product for diarrhea, after heavy impassability: semen raphani five money, root of herbaceous peony medicine three money, rhubarb, a money costus five points. The water decoction. (" the square pulse authentic ")

Gas was put to the wind and the secret secret: radish child (Fried), ground water, and of shittim two money at the end of the clothing. (" ShouYu god party ")

Pet-name ruby cure tuyere in silence: turnip, tooth of shittim two money. With water decoction, apply to vomit. (Zhu Zhenheng)

Attending for headaches and migraine: half of semen raphani, raw ginger half closed. And research are very fine, wring juice, into a few of musk, intranasal Chu into, migraine with or so. (the lifeline party ")

⑾ cure infantile plate of bowel gas pain: turnip Fried yellow, at the end of the study. Frankincense soup take half the money. (RenZhai attaches to visit)

⑿ to treat toothache: radish child erqi grain, to bare skin, fine grind. In human milk and, on the left side of a toothache, i.e., in the right nasal point a little, such as tooth on the right, or to the left nasal point. (the holy benevolence formulae)

[13] to treat injuries, blood stasis pain: two of semen raphani, born to grind rotten, put hot drink. (" the square pulse authentic ")

(1) each paper 】 【 Zhu Zhenheng: "cure phlegm of semen raphani, push the wall down the wall."

(2) "of materia medica", "the function of semen raphani long good gas. Living to rise, makes, spitting up is wind phlegm, wind chill, hair spots; down is phlegm asthma cough, diarrhea after heavy, stop the pain, all is the effect of the gas."

(3) "huang shu" : "too root, radish seed, flavor with sheen, so the work of lifting is fierce in the root."

(4) the: "new materia medica" turnip, can cure, but the ancients used to ginseng, the work such as god. Ginseng was out of the medicine of expansion, the solution of semen raphani ginseng, how to use and play work? Lady except for elimination of expansion, is false asthma cure also inflated, deficiency syndrome is false false like, ginseng of abrupt shot, until its catch bilge, failed to flash by, the more tend to take it out of the bulge is, although the increase of the catch bilge is the illusion of the moment, later on natural calm, but will not cure of kindness, little son and carrots with ginseng, is out of bilge can't increase, but only to disappear out of them, the expansion of this so-called phase system and each other. Or ask radish designed solutions for ginseng, one from a carrot is ginseng useless. This radish child and also don't know ginseng. Ginseng radish child, its work more god, ginseng fill gas, flash convinced will be suffered, not for check out bilge of disease, have to radish child to line the filling of gas, is vulnerable to gas flat, radish are flat of the gas and the damage of the shortage of gas, solid ginseng in the air, not ginseng to hurt the air also."

(5) "recorded in medical applications and the west" : "the radish seed, or raw or Fried, all can open yu, qi, eliminating swelling in addition to the full, this is the product of the gas, the gas breaker. Cover all medicine qi, single for a long time, no gas, it does not hurt and stir-fry for late of semen raphani, take money, every move when after dinner to disappear of qi, turn it, because it can go on diet, gas complacent its breed. If used in addition to the full open depression, and to participate, stilbene, the medicine of zc, although many long suit, also how to points on the injury is angry."

[from] the Chinese medicine dictionary

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"The Chinese material medica: semen raphani

Semen raphani medicine name 】 【

"Pinyin" Lai Fu Z ǐ

[English] Radish Seed

"Alias" turnip, reed Fu son

【 origin 】 from the Ben yan addendum of righteousness"

【 origin 】 medicinal material base source: is the seed of crucifer movement.

Latin animal plant mineral name: Raphanus sativus L

Harvesting and storage: the following 5 - August, have dried fruit fully mature harvest, lay the seed, to remove impurities, dry storage.

】 【 original form radish, annual or biennial herb erect, 30-100 cm high. Taproot, fleshy, oblong, globose or conical, skin green, white or red. Stems branched, glabrous, slightly powder frost. Base bulk leaf and lower cauline leaves pinnate half crack, 8-30 cm long, 3-5 cm wide, lobes ovate, lateral lobes 4-6 pairs, oblong, with obtuse teeth, sparse hairs; Upper leaves oblong, serrate or nearly entire. Flowers always cheats apical or altar; Sepals oblong; Petals 4, white, purple, or pink, 1.5 2 cm in diameter, obovoid, 1-1.5 mm long, with purple lines, there is 5 mm long claws; Stamens 6, 4 long 2 short; Pistil 1, ovary drill, stigma columnar. Siliqua cylindrical, 3-6 cm long, between seed constriction, the formation of spongy diaphragmatic, apex beaked 1-1.5 mm long; Seeds 1-6, ovate, slightly compressed, ca. 3 mm long, reddish brown, with fine checker. Flowering 4-5 months, fruiting may and June.

Native habitat division 】 【 China, across the country were cultivated, and a large number of cultivated varieties.

【 description 】 character test: dry seeds oval or nearly ovoid, slightly compressed, ca. 3 mm long, 2.5 mm wide. Several longitudinal surface red-brown, side ditch, end the navel, brownish round dot swelled. Use a magnifying glass to observe, all are dense reticulate. Visible qualitative hard, after the break with yellowish-white or yellow seeds, there are oily. Odourless, taste sweet, slightly bitter. It is beautiful thick and full, oily concurrently.

Microscopic identification: powder: yellow brown.

1. The seed coat palisade cells light yellow, orange, or yellow brown. Section view cell 1 column, general 10-37 mu m radial, tangential 7-12 microns, the outer wall and lateral wall of the upper thin, most of wall and wall thickening, sidewall central YouHou; Long view class polygon or polygonal surface, wall thickness 2-4 microns, intercellular layer of very fine.

2. Kind of subcutaneous skin cells form, the section view flat oblong, outer wall and sidewall shrinkage, cell line is not clear, which the palisade cells. In addition, the endosperm cells, cotyledon cells; Kind of skin epidermal cells and liquefied observation is not clear.

Seeds contain chemical composition 】 【 sinapine (sinapine) and fatty oil 30%, oil contains a large number of erucic acid, erucic acid) and linoleic acid, linoleic acid, linolenic acid, linolenic acid), also including rapeseed sterol (brassicasterol) and 22 - to hydrogen campesterol (22 - dehydrocampesterol). Another dish Fu element (raphanin).

[pharmacological action] 1. Resistant to the role of the original microbial: aqueous extract of semen raphani on staphylococcus aureus and escherichia coli has significant inhibitory effect, such as water infusion of concentricity versicolor bacterium, MAO Xu Lanshi favus bacteria, Mr Du ang microspore bacteria, rust color small spore tinea versicolor bacterium, wool small spores in bacteria and star slave cartesian bacteria have different degrees of inhibition. Radish (1 mg/ml concentration in vitro has obvious inhibitory effect to a variety of bacteria, on staphylococcus aureus, shigella, salmonella typhi and the MIC of escherichia coli, respectively for 40, 125, 125 and 200 MCG/ml.

2. Detoxification: radish pigment in vitro and bacterial toxins detoxification significantly mixed management, dilution of 1:20 0 can neutralize 5 a lethal dose of tetanus toxin, 1:500 neutralizes the 4 a lethal dose of diphtheria toxin, diluted to 1:16 00 fashion can reduce the skin necrosis of diphtheria toxin.

3. Antihypertensive effect: aqueous extract of semen raphani has obvious antihypertensive effect, rabbits, cats and dogs for anesthesia, intravenous when all can cause animal blood pressure to drop. Research for the influence of rabbit acute hypoxic pulmonary hypertension of semen raphani results show that the injection of semen raphani (1 ml rather crude drug 1 g) 0.3 1.2 ml/kg dose intravenous, can significantly reduce the experimental pulmonary hypertension, and significantly lower arterial pressure. Reduced pulmonary arterial pressure, body strength of semen raphani and phentolamine basic equal. Increasing the dose of semen raphani has failed to make the reduced pulmonary arterial pressure, body strength increase, only to extend the time of decompression, extended than phenol torah clearly show. Adopting continuous trace caused by intravenous injection can inhibit acute hypoxia pulmonary hypertension, at the same time reduce the reduce the side effects of arterial pressure.

4. Effects on cardiac hemodynamics: 4.1 the impact on the arterial pressure and heart rate: injection of semen raphani (1 ml rather crude drug 1 g) by 1.0 ml/kg intravenous anesthesia dog, can make the body of the artery systolic blood pressure (SAP), diastolic blood pressure (DAP), average arterial pressure (MAP), respectively 10.9, 13.9, 15.2 mmHg, pulmonary artery systolic pressure (SPAP), pulmonary artery diastolic pressure (DAPA), average pulmonary artery pressure (MPAP) lower 4.6, 4.3, 3.9 mmHg, respectively, compared with itself before using this drug has a very significant difference (P < 0.01). No obvious change in heart rate before and after dosing.

, effects on vascular resistance: 4.2 after injection intravenous injection of semen raphani, make body vascular resistance (SVR) and pulmonary vascular resistance (PVR) reduced obviously, SVR from 4583.5 + / - 632.45 to 3976.7 + / - 339.86 dyn. S/cm, PVR from 530.5 + / - 6.821 to 411.8 + / - 80.98 dyn. S/cm, own comparison before and after medication (P < 0.05 and P < 0.01.

4.3. Effects on cardiac hemodynamics: six dogs after intravenous injection of 1.0 mg/kg of semen raphani, cardiac output (CO), cardiac index (CI), stroke output (SV), stroke index (SI) are no obvious changes, before and after medication itself is no statistical significance (P < 0.05). Medication after an abnormal left ventricular index (LVSWI) and pulsation index (RVSWI) significantly reduced the right ventricle, LVSWI before and after medication were 40.12 + / - 2.83 and 33.2 3.88 mm; RVSWI was 5.34 + / - 0.74 and 0.74 + / - 0.52 (P < 0.01, R < 0.05).

Radish element in mice and in vitro toxicity 】 【 frog heart with mild toxicity. Aqueous extract in mice abdominal cavity injection of the median lethal dose of 127.4 g/kg (123.8 137.1), more animals than dosing l hours convulsions and death. Rats lavage daily 100, 200 and 400 g/kg, for 3 weeks, the blood picture, liver and kidney function and main organs are not seen.

[up] semen raphani: whisk to impurities, rinse dirt, remove, dried, mash it. Stir-fry Fu son: take net semen raphani, set the pot gently to micro, and has the aroma of degrees, remove and let cool.

Sexual flavour flavor 】 sheen; Gansu; Sex is flat

[to the] spleen; The stomach; Lung; E. the

Xiaoshi function attending 】 【 guide lag; Gas phlegm reduction. Staple food product and qi stagnation; Often abdominal distension full; Diarrhea; Diarrhea after heavy; Cough phlegm; Reversed flow of qi take full

【 usage and dosage 】 oral: decoct soup, 5-10 g; Or the pill, powder, appropriate use. External use: right amount, at the end of the study apply.

【 compound 】 (1) on the worth of gas cough, much sputum palpitations, salivary purulent blood: a match of semen raphani, grind, decoct soup, feed on clothing. (" bromides heart mirror ") (2) the cure whooping cough: green radish seeds, baked dry, grind fine powder. Sugar water to take a few, a number of the back. "" jiangxi traditional Chinese medicine" (12) : 1953; (3) out of phlegm and promote staining, encounter the taste hair: radish for net, steamed, drying of ginger juice soak mung bean big steamed cake balls. Take three pills each to tianjin swallow mouth, day three suits. (Fu Zi "integrated medicine" pure gold pill) (4) full cough, sputum reversed flow of qi new: Perilla, white mustard and radish. Wash and small fry, na on the break, in raw silk pouches, boil soup to drink. With the delicacies, generation of sip with tea and suffering shoulds not be too. (asaps medicine through the third keep close soup) (5) for all dyspepsia: hawthorn 6 two, divine comedy two two, each couple of pinellia, poria cocos, dried tangerine or orange peel, forsythia, radish each one or two. For at the end of the cook a cake pill as the child. Take seven, eighty balls, each food far, clear soup. (Dan brook method to protect and pill) 6 inflatable gas drum up cure: semen raphani, grind, to filter water juice, leaching sand one or two, one night, Fried dry, leaching and Fried, all seven times, as the late. Per meter YinFu a money. (" chu set check health providers ") all landowners have product for diarrhea, after heavy impassability: semen raphani five money, root of herbaceous peony medicine three money, rhubarb, a money costus five points. The water decoction. (the square pulse authentic) was put to the wind and the secret secret: radish child (Fried), ground water, and of shittim two money at the end of the clothing. Pet-name ruby "ShouYu party god treat tuyere in silence: turnip, tooth of shittim two money. With water decoction, apply to vomit. Attending Zhu Zhenheng treat wind and migraine headache; Half of semen raphani, raw ginger half closed. And research are very fine, wring juice, into a few of musk, drop a XIU into the nose. Migraine with or so. (" lifeline ") 11, to treat infantile bowel gas pain: turnip Fried yellow, at the end of the study. Frankincense soup take half the money. (" RenZhai attaches to party "), to treat toothache: radish erqi grain, to bare skin, fine grind. In human milk and, on the left side of a toothache, i.e., in the right nasal point a little, such as tooth on the right, or to the left nasal point. 13 and holy benevolence formulae, treat injuries, blood stasis pain: two of semen raphani, born to grind rotten, put hot drink. (" the square pulse authentic ")

1. Each paper 】 【 Zhu Zhenheng: semen raphani cure phlegm, have push the wall down the wall.

2. "of materia medica" : the function of semen raphani long good breath. Living to rise, makes drop, spitting up is wind phlegm, medicinal powder cold, hair spots; Down is phlegm asthma cough, diarrhea after heavy, stop the pain, all is the effect of the gas.

3. "huang shu" : radish seed, taste too root, with its sheen, so the work of lifting is fierce in the root.

4. The: "new materia medica radish, can cure, but the ancients used to ginseng, making the work such as god. Ginseng was except for expansion of drug elimination, the solution of semen raphani ginseng, how to use and play work? Lady except for elimination of expansion, is false asthma cure also inflated, deficiency syndrome is false false like, ginseng of abrupt shot, until its catch bilge, failed to flash by, the more tend to take it out of the bulge is, although the increase of asthma bilge is the illusion of the moment, later on natural calm, but will not cure good, little son and carrots with ginseng, is out of bilge can't increase, but only to disappear out of them, the expanding this so-called phase system and each other. Or ask the radish child designed solution of ginseng, a radish is ginseng unprofitable. This radish and ginseng is also did not know. Ginseng have turnip, her work more god, ginseng fill gas, flash convinced will be suffered, not for check out bilge of disease, have to radish child to line the filling of gas, is vulnerable to gas flat, radish are flat of the gas and the damage of the shortage of gas, solid ginseng in the air, not ginseng to hurt the air also.

5. "recorded in medical applications and the west" : radish seed, or raw or Fried, all have qi, yu, bilge in addition to the full, this is the product of the gas, not to break the air quality. Cover all medicine qi, single for a long time, no gas, it does not hurt and stir-fry for late of semen raphani, take money, every move when after dinner to disappear of qi, turn it, because its can go on diet, gas complacent its breed. If used in addition to the full open depression, and to participate, stilbene, the medicine of zc, although many long suit, also how to points on the injury is angry.

6. Compendium of material medica: set the son water to grind gear, spit wind phlegm; Vinegar research detumescence.

7. The daily material medica: treat jaundice and skin yellow like gold, low water hot red.

8. The spectrum with interest in the diet: cure phlegm syndromes, staining of gas drum, head wind, drowned, closed and one supplements.

[from] the Chinese material medica