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To xizhimen south street, xicheng district building to the British garden route

L airport line 1

Take the airport shuttle from the airport, the dongzhimen station transfer to metro line 2 to xizhimen direction and get off at xizhimen station, from C outbound, go straight to the east 100 meters on the right side to xizhimen south street, north to walk to the t-junction namely to the British garden 1 floor downstairs.

L airport line 2

From the capital airport take airport bus to xidan, get off at no.22, take a taxi to xizhimen south street English garden 1 floor.

L bus subway near:

106 bus GuanYuan: 107 road, express way

Bus: xizhimen south road 387, 44 road, inner ring 800, 816 road, inner ring 820, 845 road

Che zhuang: subway line two

Xizhimen subway: metro line 2

Buses and attempts: 107 road, 118 road, 701 road

Buses and north zhuang: 209 road, 375 road, 392 road

 

High cholesterol can lead to osteoarthritis

2016年11月07日

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High cholesterol can lead to osteoarthritis

The 2016-11-03

Source: health

 

Report from our correspondent on November 1, xiangya 2nd hospital of central south university published a new study results: hypercholesterolemia may cause cartilage damage, so as to increase the risk of arthritis. The study by the new exhibition, a professor at xiangya 2nd hospital orthopaedic wool with Australia in Queensland university of technology professor Yin shaw, etc. Research papers has been in the journal of the federation of American societies for experimental biology (FASEB) published online.

The group using animal model, new research suggests that high cholesterol can trigger mitochondrial excessive oxidative stress, cartilage cells and promote its apoptosis, cause the subchondral bone of the bone loss, in the end, or for the development of osteoarthritis.

Research by using two different kinds of animal models to simulate the human hypercholesterolemia. The first model is the apolipoprotein E gene knockout hypercholesterolemia (ApoE - / -) mice model, the other is a feeding with high cholesterol diet, diet induced hypercholesterolemia rats model. These two models are divided into high cholesterol diet group and normal diet group, in order to simulate knee joint, two models for knee arthritis simulation surgery. Whether mice or rats, compared with normal diet group, the high cholesterol diet group showed more severe osteoarthritis. The treatment of lower cholesterol levels and mitochondrial targeting antioxidant treatment, significantly reducing the incidence of osteoarthritis. Therefore, the research concludes that hypercholesterolemia by acting on the cell mitochondria oxidative stress mechanism and cause osteoarthritis.

"This study inject new vitality to the research of osteoarthritis, for the prevention and treatment of osteoarthritis provides a new direction." FASEB journal editor Thoru Pederson said: "before this, our focus on hypercholesterolemia on the cardiovascular and artery disease, but now we have a new discovery." New exhibition (MAO)