Contact Us

 

 

  

Address: Beijing's xizhimen south street, xicheng district

 

The British garden 1 floor. Room 824

 

Zip code: 100035

 

Telephone: 010-58562339

 

Fax: 010-58562339

 

Email address: cngjzj@163.com

 

Web site (click on the url link directly left) :

 

http://www.cngjzj.com/

 

Blog (click on the url link directly left) :

http://blog.sina.com.Cn/CNGJZJ

 

To xizhimen south street, xicheng district building to the British garden route

L airport line 1

Take the airport shuttle from the airport, the dongzhimen station transfer to metro line 2 to xizhimen direction and get off at xizhimen station, from C outbound, go straight to the east 100 meters on the right side to xizhimen south street, north to walk to the t-junction namely to the British garden 1 floor downstairs.

L airport line 2

From the capital airport take airport bus to xidan, get off at no.22, take a taxi to xizhimen south street English garden 1 floor.

L bus subway near:

106 bus GuanYuan: 107 road, express way

Bus: xizhimen south road 387, 44 road, inner ring 800, 816 road, inner ring 820, 845 road

Che zhuang: subway line two

Xizhimen subway: metro line 2

Buses and attempts: 107 road, 118 road, 701 road

Buses and north zhuang: 209 road, 375 road, 392 road

 

Your position is: Home >> newspaper >> newspaper

Curcumin reverses the drug resistance of primary liver cancer

2017年04月13日

复制链接 打印 大 中 小

<



Curcumin reverses the drug resistance of primary liver cancer



Time: 2017-04-14



Source: Chinese Medicine News Author: clothing Hillsborough




      The main crux of drug resistance in patients with liver cancer is the long-term use of anti-cancer drugs Sola Feini caused by hypoxia, and thus enhance the glycolysis. Harbin Medical University First Affiliated Hospital of liver surgery director Liu Lianxin led the completion of a major issue of "primary liver cancer chemotherapy resistance mechanism and clinical intervention strategy" found that the natural ingredients of traditional Chinese medicine turmeric curcumin and sorafenib combined Use, both can significantly enhance the efficacy of both, but also reverse the resistance of sorafenib. Recently, the subject won the 2016 annual Ministry of education national university science research outstanding achievement award natural science first prize.

      Primary liver cancer has a high degree of malignancy, rapid growth, wide range of metastasis and high recurrence rate. Currently, sorafenib is the only target drug for primary liver cancer, but its ultimate effect is not ideal and can lead to side effects. Liu Lianxin team found that sorafenib can produce tumor hypoxia microenvironment, and then induced tumor glycolysis enhanced, and ultimately reduce the efficacy, or even invalid. Turmeric extract from turmeric turmeric has the effect of lowering blood fat, anti-tumor, anti-inflammatory and anti-oxidation. Studies have shown that curcumin and its analogues can upregulate the VHL protein and help Sorafini "turn to victory". Both can improve the efficacy of patients with primary liver cancer to extend the 5-year survival rate and improve the prognosis.

      The team also at home and abroad to take the lead in the main component of traditional Chinese medicine arsenic arsenic trioxide into the treatment of primary liver cancer, and in-depth study of its mechanism of action, the best clinical mode of administration and related drug resistance "mystery". Clinical practice has proved that arsenic preparations by the slow continuous infusion of hepatic artery, liver cancer better. These findings reveal the resistance characteristics of hepatocellular carcinoma, in order to seek the traditional Chinese medicine arsenic trioxide liver cancer chemotherapy direction locked important clues and key path.