New breakthrough has been made in the research of artemisinin drugs

Chinese medicine experts report on the mechanism and safety of Chinese medicine

Huizhou daily focuses on the fifth Chinese medicine science conference on nov 9, 2018

As the saying goes, it's a three-point drug. Held on November 7, the fifth science meeting of traditional Chinese medicine, China academy of traditional Chinese medicine artemisinin research center consultant fu-long liao, 3 0 2 hospital PLA army research institute of Chinese medicine xiao river around the theme "the mechanism of action of traditional Chinese medicine and Chinese medicine safety" made a special report, this paper introduces the latest research progress of artemisinin mechanism and how to crack the security problems of traditional Chinese medicine.

Artemisinin has anti-tumor and immunomodulatory effects

Liao fulong made a special report on the mechanism of action of artemisinin and its derivatives. It is understood that liao fulong is a member of the team of tu youyou, a Nobel laureate in physiology or medicine.

Over the years, numerous articles related to artemisinin have been published by medical practitioners around the world, and studies on the anti-malarial mechanism of artemisinin-based drugs have been carried out. "The mechanism has not been particularly clear for a long time." In recent years, with the application of chemical biology in the study of the mechanism of action of artemisinin, the research of artemisinin-based drugs has made new breakthroughs, liao said. "In December 2015, Dr. Wang jigang proposed the theory of multiple targets in a paper on the mechanism of artemisinin action, which has become a general consensus in the academic world." According to liao, the parasite is "digging its own grave." "The parasite enters the bloodstream and produces heme, but artemisinin is activated by heme." Liao said that with the deepening of studies on artemisinin, artemisinin has been found to have not only anti-malarial activity, but also other pharmacological activities, such as anti-tumor and immunomodulatory effects, which have been used in the treatment of diseases such as lupus erythematosus and asthma.

The safety of traditional Chinese medicine should not be underestimated but should not be exaggerated

The safety of Chinese medicine is a concern of many citizens. In the afternoon, xiao xiaohe brought a theme report titled "the safety view and practice of traditional Chinese medicine in the new era", and put forward that we should keep pace with The Times to understand the safety situation and problems of traditional Chinese medicine.

The reporter understands that xiao xiaohe is mainly engaged in clinical pharmacology research and has made a series of innovative achievements in liver injury and safe medication of Chinese herbal medicine. "The safety of Chinese medicine should not be underestimated, but it should not be exaggerated." According to the "drug spectrum" of drug-induced liver injury in China, there are more than 100,000 suspected drug-induced liver injury cases in the national ADR center, about 95% of which are western medicine and 5% are traditional Chinese medicine, which indicates that Chinese medicine has good safety. However, the variety involved in the drug-induced liver injury of traditional Chinese medicine is numerous and scattered, and there is no risk warning, indicating that the risk prevention and control of traditional Chinese medicine is more difficult. Xiao xiaohe believes that in recent years, some adverse events of traditional Chinese medicine have emerged, which are related to safe drug use and affect the development of the traditional Chinese medicine industry.