Poisons may help us live longer

Source: health news

Recently, the second jinhai lake · world anti-aging BBS hosted by the mobile population service center of the national health and family planning commission, hosted by the world anti-aging biological medical association and co-organized by the mountain hydrologic park group was held in Beijing. BBS takes "let health bloom vitality" as the theme, and conducts research on stem cell research, the mystery of aging, nutritional health, healthy and nourishing community and other contents. Chairman of the joint chiefs of staff, among them, the anti-aging biological medical association chairman of Germany prevention and anti-aging association bain, professor klein nerd - GongKe poison excited effect principle of "interesting" speech, put forward the "substance harmful to our health, also can help us live longer" this subversive theory, and expounds in detail the poison effect the seven principles of excitement.

Principle 1: dose and effect

The concept of hormesis is summed up in one sentence: "many things that harm us can also be good for us, depending on the dose." This seemingly contradictory explanation lies in the complexity of organisms. A machine wears out over time, but a human body is more than just a machine. Living organisms have an important ability to respond to damage. All organisms, including yeasts and humans, have this self-repairing mechanism. What's more, if repeatedly damaged, the organism will develop special protection and defense mechanisms, which not only repair the damage already caused, but also prepare for future damage. From restorative medicine to preventive medicine, we're making that transition in medicine, and every cell has been doing that for a long time.

According to paracelsus, a famous 16th century doctor and founder of modern pharmacology, "dose produces poison". In principle, what is good for us becomes bad at some point as we increase the dose of it. The theory applies to any drug that becomes toxic at a high dose. In the 21st century, the principle of toxic excitatory effect tells us, and vice versa, that low-dose poisons can be turned into drugs to achieve therapeutic effects.

Rule two: eat less and live longer

For the body, too long a state of hunger will have the risk of starvation, the body will not be able to bear. But according to the toxic excitatory effect, damage can also be beneficial if it does not exceed a certain limit. Even caloric restriction can cause toxic excitatory effects in the body, activate deacetylases, repair damage in cells and DNA, and allow us to live longer.

Principle 3: the benefits of injury

Exercise is indeed healthy, there is no doubt about it. First, metabolic activity increases during exercise, but this also means an increase in the release of free radicals, a factor in aging. This may not sound like much of a health benefit, but the fact that exercise is a huge load on the body in the first place can be explained by the toxic excitatory effect. Exercise itself is not healthy, healthy is the body's response to exercise. In the face of free radicals generated by exercise, the antioxidant enzymes of the body run at a high speed, which is a typical supercompensation mechanism of toxic excitatory effect. As a result, oxidative stress is continuously reduced.

Rule 4: cancel dinner

Canceling dinner is a further stress stimulation to the body, so it fully conforms to the toxic excitatory effect, and is a special form of caloric restriction. Because intermittent cut off form, also provided the opportunity that adjusts oneself hormone to secrete for organic body. If you don't eat after 5 p.m., you'll have a mild hypoglycemia at night, which not only helps you lose weight, but also stimulates your pituitary gland to produce more growth hormone in the morning. People don't have to worry about losing their quality of life because skipping dinner twice a week has the same benefits as skipping dinner in a row.

Principle 5: toxic excitatory effect of mitochondria

The best way to make mitochondria is through exercise, which is also the result of toxic excitatory effects. Mitochondria provide energy, and people who exercise rely on them in particular ways. Exercise consumes energy. Mitochondria mainly run at high speed in muscle cells during physical activity. Under high intensity load, they will reach their limit at some point. Anyone who has experienced a feeling of exhaustion knows the result: muscle soreness, exhaustion of the body and exhaustion of energy. Why is this good? Because the body produces adaptive toxic excitatory effects on load. To avoid such energy crises in the future, the body tries to produce new mitochondria, which improve the body's functioning. The same is true in the brain, where, apart from muscle cells, brain cells consume the most energy and benefit entirely from the extra mitochondria in this particular way.

Principle 6: other options to limit calories

Red wine's resveratrol, broccoli's sulforaphane and coffee's curcumin are all new stars of nutritional medicine, and few ingredients are healthier than these. However, most of the secondary plant substances that are good for health are actually poisons. In most cases, they are the defensive substances produced by plants to resist the invasion of fungi, viruses, bacteria or parasites, and are the chemical "weapons" in the plant world. As low-dose poisons, they cause the excitatory effect of poisons in the body, activate the antioxidant enzymes of the body and capture free radicals. Deacetylase is activated for cell repair. The telomerase is stimulated, the telomeres are regenerated, and the toxic stuff is doing us good again.

Principle 7: health under radiation

Nuclear power and its risks are scary for many people, depending on the amount of radiation. For decades, people who work at nuclear power plants have been among the most highly regarded in medical research because of concerns about rising cancer rates among those who work there. Over the years, however, the results have been surprising. The incidence of cancer among nuclear power plant workers is not higher, but lower than that of the general population, showing the same results around the world. Moderate radiation can trigger the body's repair mechanism, now known as radiation-toxic excitatory effect. In particular, increased telomerase activity slows telomere breakdown and protects sensitive DNA, which not only protects against cancer, but also completely protects against aging.